Medical Assistant Salary in San Antonio, TX
Medical Assistants in the San Antonio-New Braunfels, TX metro area earn a median $39,180 a year — 14% less than the national median. After 2026 taxes, that is $33,661 take-home, or $2,805 a month.
Take-home pay calculator
Pre-filled with the median medical assistant salary in San Antonio, TX. Enter your own offer to see your paycheck.
- Federal income tax$2,522
- Social Security (6.2%)$2,429
- Medicare (1.45%)$568
- Texas income tax$0
- Take-home pay$33,661
Marginal rate: 12% federal + 0.00% state
Got an offer somewhere else? Compare it with this one after taxes and rent →
Medical Assistant pay by experience in San Antonio, TX
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $35,950 | $17.28 | $31,066 | $2,589 |
| 25th percentile | $37,410 | $17.99 | $32,239 | $2,687 |
| Median (50th) | $39,180 | $18.84 | $33,661 | $2,805 |
| 75th percentile | $45,250 | $21.75 | $38,538 | $3,212 |
| 90th percentile (top earners) | $46,870 | $22.53 | $39,840 | $3,320 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Texas resident, 2026 tax rules.
What $39,180 buys in San Antonio, TX
Prices in San Antonio, TX are 5.3% lower than the U.S. average (housing costs are 5% below the national average). Adjusted for local prices, a median medical assistant's $33,661 take-home pay has the buying power of $35,539 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
San Antonio, TX has 1.3× the national concentration of medical assistant jobs — a strong local market for this occupation.
Best-paying cities for medical assistants, adjusted for cost of living
San Antonio, TX ranks #51 of 63 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | Seattle, WA | $61,500 | $51,595 | $46,427 |
| 2 | Sacramento, CA | $61,970 | $49,400 | $46,311 |
| 3 | San Jose, CA | $61,940 | $49,378 | $44,717 |
| 4 | Milwaukee, WI | $49,590 | $40,625 | $41,908 |
| 5 | San Francisco, CA | $59,790 | $47,807 | $41,351 |
| 6 | Portland, OR | $56,240 | $43,277 | $41,052 |
| 7 | Minneapolis, MN | $52,570 | $42,369 | $40,420 |
| 8 | Kansas City, MO | $45,300 | $37,387 | $40,399 |
| 51 | San Antonio, TX | $39,180 | $33,661 | $35,539 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 63 metros →
About the job: medical assistants
Perform administrative and certain clinical duties under the direction of a physician. Administrative duties may include scheduling appointments, maintaining medical records, billing, and coding information for insurance purposes. Clinical duties may include taking and recording vital signs and medical histories, preparing patients for examination, drawing blood, and administering medications as directed by physician.
- Typical education
- Postsecondary nondegree award
- Work experience
- None required
- On-the-job training
- None
- Job outlook, 2025–35
- +12.9% (much faster than average)
Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.
Medical Assistant salaries elsewhere in Texas
- Austin, TX — $45,820
- Houston, TX — $42,110
- Dallas, TX — $43,100
- McAllen, TX — $34,810
Frequently asked questions
How much does a medical assistant make in San Antonio, TX?
The median medical assistant salary in the San Antonio-New Braunfels, TX metro area is $39,180 a year, or about $18.84 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $37,410 and $45,250.
What is a medical assistant’s take-home pay in San Antonio, TX?
On the median $39,180 salary, a single filer living in Texas takes home about $33,661 a year ($2,805 a month) after federal tax, Social Security, Medicare in 2026.
Is San Antonio, TX a good place to work as a medical assistant?
Pay here is 14% below the national median of $45,690. Local prices are 5.3% below the U.S. average, so the take-home pay buys what $35,539 would in a typical U.S. city. San Antonio, TX ranks #51 of 63 metro areas for cost-of-living-adjusted pay in this job.
Can a medical assistant afford rent in San Antonio, TX?
HUD’s fair market rent for a one-bedroom in San Antonio, TX is $1,171 a month ($1,419 for two bedrooms) — 42% of a median medical assistant’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in San Antonio, TX
- Dental Assistant — $45,920
- Nursing Assistant — $36,800
- Home Health and Personal Care Aide — $25,960