Medical Secretary and Administrative Assistant Salary in San Antonio, TX
Medical Secretaries and Administrative Assistants in the San Antonio-New Braunfels, TX metro area earn a median $42,560 a year — 7% less than the national median. After 2026 taxes, that is $36,377 take-home, or $3,031 a month.
Take-home pay calculator
Pre-filled with the median medical secretary and administrative assistant salary in San Antonio, TX. Enter your own offer to see your paycheck.
- Federal income tax$2,927
- Social Security (6.2%)$2,639
- Medicare (1.45%)$617
- Texas income tax$0
- Take-home pay$36,377
Marginal rate: 12% federal + 0.00% state
Got an offer somewhere else? Compare it with this one after taxes and rent →
Medical Secretary and Administrative Assistant pay by experience in San Antonio, TX
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $35,610 | $17.12 | $30,793 | $2,566 |
| 25th percentile | $37,510 | $18.03 | $32,319 | $2,693 |
| Median (50th) | $42,560 | $20.46 | $36,377 | $3,031 |
| 75th percentile | $46,430 | $22.32 | $39,487 | $3,291 |
| 90th percentile (top earners) | $55,040 | $26.46 | $46,405 | $3,867 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Texas resident, 2026 tax rules.
What $42,560 buys in San Antonio, TX
Prices in San Antonio, TX are 5.3% lower than the U.S. average (housing costs are 5% below the national average). Adjusted for local prices, a median medical secretary and administrative assistant's $36,377 take-home pay has the buying power of $38,406 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Medical Secretary and Administrative Assistant jobs are about as common in San Antonio, TX as in the U.S. overall (location quotient 1.05).
Best-paying cities for medical secretaries and administrative assistants, adjusted for cost of living
San Antonio, TX ranks #27 of 69 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $69,350 | $54,380 | $49,247 |
| 2 | Seattle, WA | $60,350 | $50,671 | $45,595 |
| 3 | Sacramento, CA | $57,730 | $46,302 | $43,407 |
| 4 | San Francisco, CA | $61,330 | $48,932 | $42,324 |
| 5 | Winston, NC | $46,370 | $38,097 | $41,390 |
| 6 | Cleveland, OH | $45,920 | $38,596 | $41,094 |
| 7 | Albuquerque, NM | $47,310 | $39,127 | $40,950 |
| 8 | Cincinnati, OH | $46,180 | $38,798 | $40,682 |
| 27 | San Antonio, TX | $42,560 | $36,377 | $38,406 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 69 metros →
About the job: medical secretaries and administrative assistants
Perform secretarial duties using specific knowledge of medical terminology and hospital, clinic, or laboratory procedures. Duties may include scheduling appointments, billing patients, and compiling and recording medical charts, reports, and correspondence.
- Typical education
- High school diploma or equivalent
- Work experience
- None required
- On-the-job training
- Moderate-term on-the-job training
- Job outlook, 2025–35
- +4.8% (about average)
Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.
Medical Secretary and Administrative Assistant salaries elsewhere in Texas
- Austin, TX — $46,510
- Houston, TX — $44,210
- Dallas, TX — $45,630
Frequently asked questions
How much does a medical secretary and administrative assistant make in San Antonio, TX?
The median medical secretary and administrative assistant salary in the San Antonio-New Braunfels, TX metro area is $42,560 a year, or about $20.46 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $37,510 and $46,430.
What is a medical secretary and administrative assistant’s take-home pay in San Antonio, TX?
On the median $42,560 salary, a single filer living in Texas takes home about $36,377 a year ($3,031 a month) after federal tax, Social Security, Medicare in 2026.
Is San Antonio, TX a good place to work as a medical secretary and administrative assistant?
Pay here is 7% below the national median of $45,930. Local prices are 5.3% below the U.S. average, so the take-home pay buys what $38,406 would in a typical U.S. city. San Antonio, TX ranks #27 of 69 metro areas for cost-of-living-adjusted pay in this job.
Can a medical secretary and administrative assistant afford rent in San Antonio, TX?
HUD’s fair market rent for a one-bedroom in San Antonio, TX is $1,171 a month ($1,419 for two bedrooms) — 39% of a median medical secretary and administrative assistant’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in San Antonio, TX
- First-Line Supervisor of Office and Administrative Support Workers — $63,850
- Production, Planning, and Expediting Clerks — $56,040
- Insurance Claim and Policy Processing Clerk — $55,910
- Bookkeeping, Accounting, and Auditing Clerks — $48,150
- Shipping, Receiving, and Inventory Clerks — $43,750
- Secretaries and Administrative Assistants, Except Legal, Medical, and Executive — $43,440
- Billing and Posting Clerk — $43,340
- Customer Service Representative — $42,720
- Office Clerks, General — $38,860
- Receptionist and Information Clerk — $36,550