Updated · 2026 tax rules · Data: IRS, BLS, BEA, HUD · How we calculate

Pharmacist Salary in San Diego, CA

Pharmacists in the San Diego-Chula Vista-Carlsbad, CA metro area earn a median $165,130 a year — 17% more than the national median. After 2026 taxes, that is $110,858 take-home, or $9,238 a month.

Median salary
$165,130
$79.39 per hour
Typical range
$131,400 – $214,480
10th to 90th percentile
Jobs in San Diego, CA
2,840
0.89× national concentration
▲0.8%
Pay trend: The median for pharmacists in San Diego, CA rose from $163,860 (May 2024) to $165,130 (May 2025). That trailed inflation (2.4%), so buying power slipped about 1.6%.

Take-home pay calculator

Pre-filled with the median pharmacist salary in San Diego, CA. Enter your own offer to see your paycheck.

Pharmacist in San Diego, CA
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$110,858
per year · effective tax rate 32.9%
$9,238Monthly
$4,619Twice a month
$4,264Every 2 weeks
$53.30Hourly
  • Federal income tax$28,365
  • Social Security (6.2%)$10,238
  • Medicare (1.45%)$2,394
  • California income tax$11,128
  • CA State Disability Insurance (SDI)$2,147
  • Take-home pay$110,858

Marginal rate: 24% federal + 9.30% state

Got an offer somewhere else? Compare it with this one after taxes and rent →

Pharmacist pay by experience in San Diego, CA

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$131,400$63.17$91,379$7,615
25th percentile$154,000$74.04$104,431$8,703
Median (50th)$165,130$79.39$110,858$9,238
75th percentile$201,750$97.00$133,060$11,088
90th percentile (top earners)$214,480$103.12$141,086$11,757

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, California resident, 2026 tax rules.

What $165,130 buys in San Diego, CA

Prices in San Diego, CA are 11.9% higher than the U.S. average (housing costs are 1.79× the national average). Adjusted for local prices, a median pharmacist's $110,858 take-home pay has the buying power of $99,080 in a typical American city.

1-bedroom rent
$2,459
27% of monthly take-home
2-bedroom rent
$3,001
32% of monthly take-home
Left after 1-BR rent
$6,779
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Pharmacist jobs are about as common in San Diego, CA as in the U.S. overall (location quotient 0.89).

Best-paying cities for pharmacists, adjusted for cost of living

San Diego, CA ranks #22 of 29 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Charlotte, NC $150,580$108,688$111,649
2Cleveland, OH $140,690$104,341$111,092
3Seattle, WA $162,870$122,588$110,307
4Nashville, TN $137,590$105,309$109,312
5Kansas City, MO $139,460$100,970$109,106
6Cincinnati, OH $140,200$104,020$109,069
7Houston, TX $140,470$107,277$108,768
8Denver, CO $157,890$112,945$106,772
22San Diego, CA$165,130$110,858$99,080

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 29 metros →

About the job: pharmacists

Dispense drugs prescribed by physicians and other health practitioners and provide information to patients about medications and their use. May advise physicians and other health practitioners on the selection, dosage, interactions, and side effects of medications.

Typical education
Doctoral or professional degree
Work experience
None required
On-the-job training
None
Job outlook, 2025–35
+5.2% (faster than average)

Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.

Pharmacist salaries elsewhere in California

Frequently asked questions

How much does a pharmacist make in San Diego, CA?

The median pharmacist salary in the San Diego-Chula Vista-Carlsbad, CA metro area is $165,130 a year, or about $79.39 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $154,000 and $201,750.

What is a pharmacist’s take-home pay in San Diego, CA?

On the median $165,130 salary, a single filer living in California takes home about $110,858 a year ($9,238 a month) after federal tax, Social Security, Medicare and $13,274 in California taxes in 2026.

Is San Diego, CA a good place to work as a pharmacist?

Pay here is 17% above the national median of $140,910. Local prices are 11.9% above the U.S. average, so the take-home pay buys what $99,080 would in a typical U.S. city. San Diego, CA ranks #22 of 29 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in San Diego, CA?

HUD’s fair market rent for a one-bedroom in San Diego, CA is $2,459 a month ($3,001 for two bedrooms) — 27% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in San Diego, CA

Cost of living & all salaries in San Diego, CA →