Updated · 2026 tax rules · Data: IRS, BLS, BEA, HUD · How we calculate

Pharmacist Salary in Denver, CO

Pharmacists in the Denver-Aurora-Centennial, CO metro area earn a median $157,890 a year — 12% more than the national median. After 2026 taxes, that is $112,945 take-home, or $9,412 a month.

Median salary
$157,890
$75.91 per hour
Typical range
$122,450 – $188,490
10th to 90th percentile
Jobs in Denver, CO
2,630
0.79× national concentration
▲3.7%
Pay trend: The median for pharmacists in Denver, CO rose from $152,200 (May 2024) to $157,890 (May 2025). That beat inflation (2.4%), a real raise of about 1.3%.

Take-home pay calculator

Pre-filled with the median pharmacist salary in Denver, CO. Enter your own offer to see your paycheck.

Pharmacist in Denver, CO
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$112,945
per year · effective tax rate 28.5%
$9,412Monthly
$4,706Twice a month
$4,344Every 2 weeks
$54.30Hourly
  • Federal income tax$26,628
  • Social Security (6.2%)$9,789
  • Medicare (1.45%)$2,289
  • Colorado income tax$6,239
  • Take-home pay$112,945

Marginal rate: 24% federal + 4.40% state

Got an offer somewhere else? Compare it with this one after taxes and rent →

Pharmacist pay by experience in Denver, CO

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$122,450$58.87$90,281$7,523
25th percentile$137,550$66.13$99,938$8,328
Median (50th)$157,890$75.91$112,945$9,412
75th percentile$169,230$81.36$120,197$10,016
90th percentile (top earners)$188,490$90.62$132,761$11,063

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Colorado resident, 2026 tax rules.

What $157,890 buys in Denver, CO

Prices in Denver, CO are 5.8% higher than the U.S. average (housing costs are 1.47× the national average). Adjusted for local prices, a median pharmacist's $112,945 take-home pay has the buying power of $106,772 in a typical American city.

1-bedroom rent
$1,754
19% of monthly take-home
2-bedroom rent
$2,089
22% of monthly take-home
Left after 1-BR rent
$7,658
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Pharmacist jobs are less concentrated in Denver, CO than nationally (location quotient 0.79), so openings may be scarcer.

Best-paying cities for pharmacists, adjusted for cost of living

Denver, CO ranks #8 of 29 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Charlotte, NC $150,580$108,688$111,649
2Cleveland, OH $140,690$104,341$111,092
3Seattle, WA $162,870$122,588$110,307
4Nashville, TN $137,590$105,309$109,312
5Kansas City, MO $139,460$100,970$109,106
6Cincinnati, OH $140,200$104,020$109,069
7Houston, TX $140,470$107,277$108,768
8Denver, CO $157,890$112,945$106,772

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 29 metros →

About the job: pharmacists

Dispense drugs prescribed by physicians and other health practitioners and provide information to patients about medications and their use. May advise physicians and other health practitioners on the selection, dosage, interactions, and side effects of medications.

Typical education
Doctoral or professional degree
Work experience
None required
On-the-job training
None
Job outlook, 2025–35
+5.2% (faster than average)

Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.

Frequently asked questions

How much does a pharmacist make in Denver, CO?

The median pharmacist salary in the Denver-Aurora-Centennial, CO metro area is $157,890 a year, or about $75.91 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $137,550 and $169,230.

What is a pharmacist’s take-home pay in Denver, CO?

On the median $157,890 salary, a single filer living in Colorado takes home about $112,945 a year ($9,412 a month) after federal tax, Social Security, Medicare and $6,239 in Colorado taxes in 2026.

Is Denver, CO a good place to work as a pharmacist?

Pay here is 12% above the national median of $140,910. Local prices are 5.8% above the U.S. average, so the take-home pay buys what $106,772 would in a typical U.S. city. Denver, CO ranks #8 of 29 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in Denver, CO?

HUD’s fair market rent for a one-bedroom in Denver, CO is $1,754 a month ($2,089 for two bedrooms) — 19% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

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Cost of living & all salaries in Denver, CO →