Updated · 2026 tax rules · Data: IRS, BLS, BEA, HUD · How we calculate

Medical Secretary and Administrative Assistant Salary in Indianapolis, IN

Medical Secretaries and Administrative Assistants in the Indianapolis-Carmel-Greenwood, IN metro area earn a median $46,030 a year — 0% more than the national median. After 2026 taxes, that is $37,837 take-home, or $3,153 a month.

Median salary
$46,030
$22.13 per hour
Typical range
$37,200 – $58,200
10th to 90th percentile
Jobs in Indianapolis, IN
8,260
1.21× national concentration
▲4.3%
Pay trend: The median for medical secretaries and administrative assistants in Indianapolis, IN rose from $44,120 (May 2024) to $46,030 (May 2025). That beat inflation (2.4%), a real raise of about 1.9%.

Take-home pay calculator

Pre-filled with the median medical secretary and administrative assistant salary in Indianapolis, IN. Enter your own offer to see your paycheck.

Medical Secretary and Administrative Assistant in Indianapolis, IN
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$37,837
per year · effective tax rate 17.8%
$3,153Monthly
$1,577Twice a month
$1,455Every 2 weeks
$18.19Hourly
  • Federal income tax$3,344
  • Social Security (6.2%)$2,854
  • Medicare (1.45%)$667
  • Indiana income tax$1,328
  • Take-home pay$37,837

Marginal rate: 12% federal + 2.95% state

Living in Indianapolis (Marion County)? City residents also pay Indianapolis (Marion County)’s County income tax — about $910 a year on this salary — which lowers take-home pay to $36,927 ($3,077 a month). Choose “Indianapolis (Marion County)” under City income tax in the calculator. Suburban residents usually don’t pay it.

Got an offer somewhere else? Compare it with this one after taxes and rent →

Medical Secretary and Administrative Assistant pay by experience in Indianapolis, IN

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$37,200$17.88$31,002$2,584
25th percentile$38,680$18.60$32,148$2,679
Median (50th)$46,030$22.13$37,837$3,153
75th percentile$47,740$22.95$39,160$3,263
90th percentile (top earners)$58,200$27.98$47,256$3,938

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Indiana resident, 2026 tax rules.

What $46,030 buys in Indianapolis, IN

Prices in Indianapolis, IN are 4.3% lower than the U.S. average (housing costs are 11% below the national average). Adjusted for local prices, a median medical secretary and administrative assistant's $37,837 take-home pay has the buying power of $39,538 in a typical American city.

1-bedroom rent
$1,242
39% of monthly take-home
2-bedroom rent
$1,454
46% of monthly take-home
Left after 1-BR rent
$1,911
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Indianapolis, IN has 1.2× the national concentration of medical secretary and administrative assistant jobs — a strong local market for this occupation.

Best-paying cities for medical secretaries and administrative assistants, adjusted for cost of living

Indianapolis, IN ranks #17 of 69 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1San Jose, CA $69,350$54,380$49,247
2Seattle, WA $60,350$50,671$45,595
3Sacramento, CA $57,730$46,302$43,407
4San Francisco, CA $61,330$48,932$42,324
5Winston, NC $46,370$38,097$41,390
6Cleveland, OH $45,920$38,596$41,094
7Albuquerque, NM $47,310$39,127$40,950
8Cincinnati, OH $46,180$38,798$40,682
17Indianapolis, IN$46,030$37,837$39,538

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 69 metros →

About the job: medical secretaries and administrative assistants

Perform secretarial duties using specific knowledge of medical terminology and hospital, clinic, or laboratory procedures. Duties may include scheduling appointments, billing patients, and compiling and recording medical charts, reports, and correspondence.

Typical education
High school diploma or equivalent
Work experience
None required
On-the-job training
Moderate-term on-the-job training
Job outlook, 2025–35
+4.8% (about average)

Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.

Frequently asked questions

How much does a medical secretary and administrative assistant make in Indianapolis, IN?

The median medical secretary and administrative assistant salary in the Indianapolis-Carmel-Greenwood, IN metro area is $46,030 a year, or about $22.13 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $38,680 and $47,740.

What is a medical secretary and administrative assistant’s take-home pay in Indianapolis, IN?

On the median $46,030 salary, a single filer living in Indiana takes home about $37,837 a year ($3,153 a month) after federal tax, Social Security, Medicare and $1,328 in Indiana taxes in 2026.

Is Indianapolis, IN a good place to work as a medical secretary and administrative assistant?

Pay here is 0% above the national median of $45,930. Local prices are 4.3% below the U.S. average, so the take-home pay buys what $39,538 would in a typical U.S. city. Indianapolis, IN ranks #17 of 69 metro areas for cost-of-living-adjusted pay in this job.

Can a medical secretary and administrative assistant afford rent in Indianapolis, IN?

HUD’s fair market rent for a one-bedroom in Indianapolis, IN is $1,242 a month ($1,454 for two bedrooms) — 39% of a median medical secretary and administrative assistant’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

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