Registered Nurse Salary in San Antonio, TX
Registered Nurses in the San Antonio-New Braunfels, TX metro area earn a median $94,370 a year — 3% less than the national median. After 2026 taxes, that is $75,219 take-home, or $6,268 a month.
Take-home pay calculator
Pre-filled with the median registered nurse salary in San Antonio, TX. Enter your own offer to see your paycheck.
- Federal income tax$11,931
- Social Security (6.2%)$5,851
- Medicare (1.45%)$1,368
- Texas income tax$0
- Take-home pay$75,219
Marginal rate: 22% federal + 0.00% state
Got an offer somewhere else? Compare it with this one after taxes and rent →
Registered Nurse pay by experience in San Antonio, TX
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $66,430 | $31.94 | $55,557 | $4,630 |
| 25th percentile | $78,100 | $37.55 | $63,773 | $5,314 |
| Median (50th) | $94,370 | $45.37 | $75,219 | $6,268 |
| 75th percentile | $100,760 | $48.44 | $79,715 | $6,643 |
| 90th percentile (top earners) | $122,990 | $59.13 | $95,330 | $7,944 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Texas resident, 2026 tax rules.
What $94,370 buys in San Antonio, TX
Prices in San Antonio, TX are 5.3% lower than the U.S. average (housing costs are 5% below the national average). Adjusted for local prices, a median registered nurse's $75,219 take-home pay has the buying power of $79,416 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Registered Nurse jobs are about as common in San Antonio, TX as in the U.S. overall (location quotient 0.97).
Best-paying cities for registered nurses, adjusted for cost of living
San Antonio, TX ranks #37 of 206 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $216,740 | $142,511 | $129,059 |
| 2 | Vallejo, CA | $203,290 | $134,031 | $123,555 |
| 3 | Santa Rosa, CA | $174,550 | $116,298 | $107,899 |
| 4 | Sacramento, CA | $171,460 | $114,514 | $107,353 |
| 5 | San Francisco, CA | $186,610 | $123,394 | $106,730 |
| 6 | Bend, OR | $135,010 | $92,480 | $89,260 |
| 7 | Bakersfield, CA | $128,810 | $89,883 | $89,094 |
| 8 | Seattle, WA | $128,260 | $98,932 | $89,021 |
| 37 | San Antonio, TX | $94,370 | $75,219 | $79,416 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 206 metros →
About the job: registered nurses
Assess patient health problems and needs, develop and implement nursing care plans, and maintain medical records. Administer nursing care to ill, injured, convalescent, or disabled patients. May advise patients on health maintenance and disease prevention or provide case management. Licensing or registration required.
- Typical education
- Bachelor's degree
- Work experience
- None required
- On-the-job training
- None
- Job outlook, 2025–35
- +5.6% (faster than average)
Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.
Registered Nurse salaries elsewhere in Texas
- Killeen, TX — $93,440
- Houston, TX — $99,830
- Waco, TX — $92,890
- Austin, TX — $97,890
- Dallas, TX — $101,420
- El Paso, TX — $86,100
- Brownsville, TX — $81,090
- McAllen, TX — $80,540
Frequently asked questions
How much does a registered nurse make in San Antonio, TX?
The median registered nurse salary in the San Antonio-New Braunfels, TX metro area is $94,370 a year, or about $45.37 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $78,100 and $100,760.
What is a registered nurse’s take-home pay in San Antonio, TX?
On the median $94,370 salary, a single filer living in Texas takes home about $75,219 a year ($6,268 a month) after federal tax, Social Security, Medicare in 2026.
Is San Antonio, TX a good place to work as a registered nurse?
Pay here is 3% below the national median of $97,550. Local prices are 5.3% below the U.S. average, so the take-home pay buys what $79,416 would in a typical U.S. city. San Antonio, TX ranks #37 of 206 metro areas for cost-of-living-adjusted pay in this job.
Can a registered nurse afford rent in San Antonio, TX?
HUD’s fair market rent for a one-bedroom in San Antonio, TX is $1,171 a month ($1,419 for two bedrooms) — 19% of a median registered nurse’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in San Antonio, TX
- Licensed Practical and Licensed Vocational Nurse — $62,280
- Clinical Laboratory Technologist and Technician — $61,010
- Pharmacy Technician — $47,050