Pharmacist Salary in San Diego, CA

Pharmacists in the San Diego-Chula Vista-Carlsbad, CA metro area earn a median $165,130 a year — 17% more than the national median. After 2026 taxes, that is $110,858 take-home, or $9,238 a month.

Median salary
$165,130
$79.39 per hour
Typical range
$131,400 – $214,480
10th to 90th percentile
Jobs in San Diego, CA
2,840
0.89× national concentration

Take-home pay calculator

Pre-filled with the median pharmacist salary in San Diego, CA. Enter your own offer to see your paycheck.

Pharmacist in San Diego, CA
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$110,858
per year · effective tax rate 32.9%
$9,238Monthly
$4,619Twice a month
$4,264Every 2 weeks
$53.30Hourly
  • Federal income tax$28,365
  • Social Security (6.2%)$10,238
  • Medicare (1.45%)$2,394
  • California income tax$11,128
  • CA State Disability Insurance (SDI)$2,147
  • Take-home pay$110,858

Marginal rate: 24% federal + 9.30% state

Pharmacist pay by experience in San Diego, CA

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$131,400$63.17$91,379$7,615
25th percentile$154,000$74.04$104,431$8,703
Median (50th)$165,130$79.39$110,858$9,238
75th percentile$201,750$97.00$133,060$11,088
90th percentile (top earners)$214,480$103.12$141,086$11,757

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, California resident, 2026 tax rules.

What $165,130 buys in San Diego, CA

Prices in San Diego, CA are 11.9% higher than the U.S. average (housing costs are 1.79× the national average). Adjusted for local prices, a median pharmacist's $110,858 take-home pay has the buying power of $99,080 in a typical American city.

1-bedroom rent
$2,459
27% of monthly take-home
2-bedroom rent
$3,001
32% of monthly take-home
Left after 1-BR rent
$6,779
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Pharmacist jobs are about as common in San Diego, CA as in the U.S. overall (location quotient 0.89).

Best-paying cities for pharmacists, adjusted for cost of living

San Diego, CA ranks #105 of 120 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Rochester, MN $164,250$113,470$124,938
2Sioux Falls, SD $148,330$112,650$124,295
3McAllen, TX $137,700$105,384$122,689
4San Antonio, TX $150,500$114,133$120,500
5Shreveport, LA $137,970$101,816$120,114
6San Jose, CA $199,040$131,343$118,945
7Spartanburg, SC $153,610$108,199$118,833
8Fargo, ND $142,040$106,840$117,573
105San Diego, CA$165,130$110,858$99,080

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →

Pharmacist salaries elsewhere in California

Frequently asked questions

How much does a pharmacist make in San Diego, CA?

The median pharmacist salary in the San Diego-Chula Vista-Carlsbad, CA metro area is $165,130 a year, or about $79.39 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $154,000 and $201,750.

What is a pharmacist’s take-home pay in San Diego, CA?

On the median $165,130 salary, a single filer living in California takes home about $110,858 a year ($9,238 a month) after federal tax, Social Security, Medicare and $13,274 in California taxes in 2026.

Is San Diego, CA a good place to work as a pharmacist?

Pay here is 17% above the national median of $140,910. Local prices are 11.9% above the U.S. average, so the take-home pay buys what $99,080 would in a typical U.S. city. San Diego, CA ranks #105 of 120 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in San Diego, CA?

HUD’s fair market rent for a one-bedroom in San Diego, CA is $2,459 a month ($3,001 for two bedrooms) — 27% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in San Diego, CA

Cost of living & all salaries in San Diego, CA →