Pharmacist Salary in San Antonio, TX

Pharmacists in the San Antonio-New Braunfels, TX metro area earn a median $150,500 a year — 7% more than the national median. After 2026 taxes, that is $114,133 take-home, or $9,511 a month.

Median salary
$150,500
$72.36 per hour
Typical range
$96,670 – $167,100
10th to 90th percentile
Jobs in San Antonio, TX
2,260
0.97× national concentration

Take-home pay calculator

Pre-filled with the median pharmacist salary in San Antonio, TX. Enter your own offer to see your paycheck.

Pharmacist in San Antonio, TX
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$114,133
per year · effective tax rate 24.2%
$9,511Monthly
$4,756Twice a month
$4,390Every 2 weeks
$54.87Hourly
  • Federal income tax$24,854
  • Social Security (6.2%)$9,331
  • Medicare (1.45%)$2,182
  • Texas income tax$0
  • Take-home pay$114,133

Marginal rate: 24% federal + 0.00% state

Pharmacist pay by experience in San Antonio, TX

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$96,670$46.48$76,837$6,403
25th percentile$132,950$63.92$102,137$8,511
Median (50th)$150,500$72.36$114,133$9,511
75th percentile$158,870$76.38$119,854$9,988
90th percentile (top earners)$167,100$80.34$125,479$10,457

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Texas resident, 2026 tax rules.

What $150,500 buys in San Antonio, TX

Prices in San Antonio, TX are 5.3% lower than the U.S. average (housing costs are 5% below the national average). Adjusted for local prices, a median pharmacist's $114,133 take-home pay has the buying power of $120,500 in a typical American city.

1-bedroom rent
$1,171
12% of monthly take-home
2-bedroom rent
$1,419
15% of monthly take-home
Left after 1-BR rent
$8,340
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Pharmacist jobs are about as common in San Antonio, TX as in the U.S. overall (location quotient 0.97).

Best-paying cities for pharmacists, adjusted for cost of living

San Antonio, TX ranks #4 of 120 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Rochester, MN $164,250$113,470$124,938
2Sioux Falls, SD $148,330$112,650$124,295
3McAllen, TX $137,700$105,384$122,689
4San Antonio, TX $150,500$114,133$120,500
5Shreveport, LA $137,970$101,816$120,114
6San Jose, CA $199,040$131,343$118,945
7Spartanburg, SC $153,610$108,199$118,833
8Fargo, ND $142,040$106,840$117,573

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →

Pharmacist salaries elsewhere in Texas

Frequently asked questions

How much does a pharmacist make in San Antonio, TX?

The median pharmacist salary in the San Antonio-New Braunfels, TX metro area is $150,500 a year, or about $72.36 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $132,950 and $158,870.

What is a pharmacist’s take-home pay in San Antonio, TX?

On the median $150,500 salary, a single filer living in Texas takes home about $114,133 a year ($9,511 a month) after federal tax, Social Security, Medicare in 2026.

Is San Antonio, TX a good place to work as a pharmacist?

Pay here is 7% above the national median of $140,910. Local prices are 5.3% below the U.S. average, so the take-home pay buys what $120,500 would in a typical U.S. city. San Antonio, TX ranks #4 of 120 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in San Antonio, TX?

HUD’s fair market rent for a one-bedroom in San Antonio, TX is $1,171 a month ($1,419 for two bedrooms) — 12% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in San Antonio, TX

Cost of living & all salaries in San Antonio, TX →