Registered Nurse Salary in San Antonio, TX
Registered Nurses in the San Antonio-New Braunfels, TX metro area earn a median $94,370 a year — 3% less than the national median. After 2026 taxes, that is $75,219 take-home, or $6,268 a month.
Take-home pay calculator
Pre-filled with the median registered nurse salary in San Antonio, TX. Enter your own offer to see your paycheck.
- Federal income tax$11,931
- Social Security (6.2%)$5,851
- Medicare (1.45%)$1,368
- Texas income tax$0
- Take-home pay$75,219
Marginal rate: 22% federal + 0.00% state
Registered Nurse pay by experience in San Antonio, TX
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $66,430 | $31.94 | $55,557 | $4,630 |
| 25th percentile | $78,100 | $37.55 | $63,773 | $5,314 |
| Median (50th) | $94,370 | $45.37 | $75,219 | $6,268 |
| 75th percentile | $100,760 | $48.44 | $79,715 | $6,643 |
| 90th percentile (top earners) | $122,990 | $59.13 | $95,330 | $7,944 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Texas resident, 2026 tax rules.
What $94,370 buys in San Antonio, TX
Prices in San Antonio, TX are 5.3% lower than the U.S. average (housing costs are 5% below the national average). Adjusted for local prices, a median registered nurse's $75,219 take-home pay has the buying power of $79,416 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Registered Nurse jobs are about as common in San Antonio, TX as in the U.S. overall (location quotient 0.97).
Best-paying cities for registered nurses, adjusted for cost of living
San Antonio, TX ranks #59 of 370 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $216,740 | $142,511 | $129,059 |
| 2 | Vallejo, CA | $203,290 | $134,031 | $123,555 |
| 3 | Santa Rosa, CA | $174,550 | $116,298 | $107,899 |
| 4 | Sacramento, CA | $171,460 | $114,514 | $107,353 |
| 5 | San Francisco, CA | $186,610 | $123,394 | $106,730 |
| 6 | Santa Cruz, CA | $170,960 | $114,225 | $103,939 |
| 7 | Yuba City, CA | $149,320 | $101,728 | $97,597 |
| 8 | Olympia, WA | $125,020 | $96,717 | $93,293 |
| 59 | San Antonio, TX | $94,370 | $75,219 | $79,416 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 370 metros →
Registered Nurse salaries elsewhere in Texas
- Killeen, TX — $93,440
- Houston, TX — $99,830
- Waco, TX — $92,890
- Austin, TX — $97,890
- Texarkana, TX — $80,610
- Dallas, TX — $101,420
- El Paso, TX — $86,100
- Brownsville, TX — $81,090
Frequently asked questions
How much does a registered nurse make in San Antonio, TX?
The median registered nurse salary in the San Antonio-New Braunfels, TX metro area is $94,370 a year, or about $45.37 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $78,100 and $100,760.
What is a registered nurse’s take-home pay in San Antonio, TX?
On the median $94,370 salary, a single filer living in Texas takes home about $75,219 a year ($6,268 a month) after federal tax, Social Security, Medicare in 2026.
Is San Antonio, TX a good place to work as a registered nurse?
Pay here is 3% below the national median of $97,550. Local prices are 5.3% below the U.S. average, so the take-home pay buys what $79,416 would in a typical U.S. city. San Antonio, TX ranks #59 of 370 metro areas for cost-of-living-adjusted pay in this job.
Can a registered nurse afford rent in San Antonio, TX?
HUD’s fair market rent for a one-bedroom in San Antonio, TX is $1,171 a month ($1,419 for two bedrooms) — 19% of a median registered nurse’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in San Antonio, TX
- Physicians, All Other — $239,200+
- Family Medicine Physician — $233,780
- Dentists, General — $162,140
- Pharmacist — $150,500
- Physician Assistant — $140,160
- Nurse Practitioner — $131,770
- Veterinarian — $128,550
- Optometrist — $111,780
- Occupational Therapist — $107,650
- Physical Therapist — $106,010
- Dental Hygienist — $98,480
- Speech-Language Pathologist — $92,700