Updated · 2026 tax rules · Data: IRS, BLS, BEA, HUD · How we calculate

Registered Nurse Salary in San Francisco, CA

Registered Nurses in the San Francisco-Oakland-Fremont, CA metro area earn a median $186,610 a year — 91% more than the national median. After 2026 taxes, that is $123,394 take-home, or $10,283 a month.

Median salary
$186,610
$89.72 per hour
Typical range
$119,290 – $223,770
10th to 90th percentile
Jobs in San Francisco, CA
41,750
0.81× national concentration
▼0.7%
Pay trend: The median for registered nurses in San Francisco, CA fell from $188,020 (May 2024) to $186,610 (May 2025). That trailed inflation (2.4%), so buying power slipped about 3.1%.

Take-home pay calculator

Pre-filled with the median registered nurse salary in San Francisco, CA. Enter your own offer to see your paycheck.

Registered Nurse in San Francisco, CA
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$123,394
per year · effective tax rate 33.9%
$10,283Monthly
$5,141Twice a month
$4,746Every 2 weeks
$59.32Hourly
  • Federal income tax$33,520
  • Social Security (6.2%)$11,439
  • Medicare (1.45%)$2,706
  • California income tax$13,125
  • CA State Disability Insurance (SDI)$2,426
  • Take-home pay$123,394

Marginal rate: 24% federal + 9.30% state

Got an offer somewhere else? Compare it with this one after taxes and rent →

Registered Nurse pay by experience in San Francisco, CA

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$119,290$57.35$84,335$7,028
25th percentile$137,120$65.92$94,682$7,890
Median (50th)$186,610$89.72$123,394$10,283
75th percentile$215,630$103.67$141,811$11,818
90th percentile (top earners)$223,770$107.58$146,472$12,206

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, California resident, 2026 tax rules.

What $186,610 buys in San Francisco, CA

Prices in San Francisco, CA are 15.6% higher than the U.S. average (housing costs are 1.95× the national average). Adjusted for local prices, a median registered nurse's $123,394 take-home pay has the buying power of $106,730 in a typical American city.

1-bedroom rent
$2,620
25% of monthly take-home
2-bedroom rent
$3,187
31% of monthly take-home
Left after 1-BR rent
$7,663
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Registered Nurse jobs are about as common in San Francisco, CA as in the U.S. overall (location quotient 0.81).

Best-paying cities for registered nurses, adjusted for cost of living

San Francisco, CA ranks #5 of 206 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1San Jose, CA $216,740$142,511$129,059
2Vallejo, CA $203,290$134,031$123,555
3Santa Rosa, CA $174,550$116,298$107,899
4Sacramento, CA $171,460$114,514$107,353
5San Francisco, CA $186,610$123,394$106,730
6Bend, OR $135,010$92,480$89,260
7Bakersfield, CA $128,810$89,883$89,094
8Seattle, WA $128,260$98,932$89,021

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 206 metros →

About the job: registered nurses

Assess patient health problems and needs, develop and implement nursing care plans, and maintain medical records. Administer nursing care to ill, injured, convalescent, or disabled patients. May advise patients on health maintenance and disease prevention or provide case management. Licensing or registration required.

Typical education
Bachelor's degree
Work experience
None required
On-the-job training
None
Job outlook, 2025–35
+5.6% (faster than average)

Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.

Registered Nurse salaries elsewhere in California

Frequently asked questions

How much does a registered nurse make in San Francisco, CA?

The median registered nurse salary in the San Francisco-Oakland-Fremont, CA metro area is $186,610 a year, or about $89.72 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $137,120 and $215,630.

What is a registered nurse’s take-home pay in San Francisco, CA?

On the median $186,610 salary, a single filer living in California takes home about $123,394 a year ($10,283 a month) after federal tax, Social Security, Medicare and $15,551 in California taxes in 2026.

Is San Francisco, CA a good place to work as a registered nurse?

Pay here is 91% above the national median of $97,550. Local prices are 15.6% above the U.S. average, so the take-home pay buys what $106,730 would in a typical U.S. city. San Francisco, CA ranks #5 of 206 metro areas for cost-of-living-adjusted pay in this job.

Can a registered nurse afford rent in San Francisco, CA?

HUD’s fair market rent for a one-bedroom in San Francisco, CA is $2,620 a month ($3,187 for two bedrooms) — 25% of a median registered nurse’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

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Cost of living & all salaries in San Francisco, CA →