Data Scientist Salary in St. Louis, MO
Data Scientists in the St. Louis, MO-IL metro area earn a median $99,600 a year — 17% less than the national median. After 2026 taxes, that is $75,155 take-home, or $6,263 a month.
Take-home pay calculator
Pre-filled with the median data scientist salary in St. Louis, MO. Enter your own offer to see your paycheck.
- Federal income tax$13,082
- Social Security (6.2%)$6,175
- Medicare (1.45%)$1,444
- Missouri income tax$3,744
- Take-home pay$75,155
Marginal rate: 22% federal + 4.70% state
The St. Louis, MO-IL metro spans Missouri, Illinois. Pick the state you live in — state income tax follows your residence.
Data Scientist pay by experience in St. Louis, MO
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $59,500 | $28.61 | $48,129 | $4,011 |
| 25th percentile | $78,280 | $37.63 | $61,158 | $5,097 |
| Median (50th) | $99,600 | $47.88 | $75,155 | $6,263 |
| 75th percentile | $130,370 | $62.68 | $95,184 | $7,932 |
| 90th percentile (top earners) | $158,310 | $76.11 | $112,968 | $9,414 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Missouri resident, 2026 tax rules.
What $99,600 buys in St. Louis, MO
Prices in St. Louis, MO are 4.9% lower than the U.S. average (housing costs are 21% below the national average). Adjusted for local prices, a median data scientist's $75,155 take-home pay has the buying power of $79,037 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Data Scientist jobs are about as common in St. Louis, MO as in the U.S. overall (location quotient 1.17).
Best-paying cities for data scientists, adjusted for cost of living
St. Louis, MO ranks #49 of 72 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | Seattle, WA | $164,740 | $123,866 | $111,457 |
| 2 | San Jose, CA | $185,080 | $122,415 | $110,860 |
| 3 | Austin, TX | $127,360 | $98,317 | $100,256 |
| 4 | Charlotte, NC | $132,460 | $97,026 | $99,669 |
| 5 | San Francisco, CA | $170,110 | $113,734 | $98,375 |
| 6 | Dallas, TX | $127,750 | $98,583 | $95,628 |
| 7 | Jacksonville, FL | $122,680 | $95,118 | $95,611 |
| 8 | Bridgeport, CT | $141,760 | $101,803 | $95,264 |
| 49 | St. Louis, MO | $99,600 | $75,155 | $79,037 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 72 metros →
Data Scientist salaries elsewhere in Missouri
- Kansas City, MO — $99,870
Frequently asked questions
How much does a data scientist make in St. Louis, MO?
The median data scientist salary in the St. Louis, MO-IL metro area is $99,600 a year, or about $47.88 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $78,280 and $130,370.
What is a data scientist’s take-home pay in St. Louis, MO?
On the median $99,600 salary, a single filer living in Missouri takes home about $75,155 a year ($6,263 a month) after federal tax, Social Security, Medicare and $3,744 in Missouri taxes in 2026.
Is St. Louis, MO a good place to work as a data scientist?
Pay here is 17% below the national median of $120,230. Local prices are 4.9% below the U.S. average, so the take-home pay buys what $79,037 would in a typical U.S. city. St. Louis, MO ranks #49 of 72 metro areas for cost-of-living-adjusted pay in this job.
Can a data scientist afford rent in St. Louis, MO?
HUD’s fair market rent for a one-bedroom in St. Louis, MO is $989 a month ($1,211 for two bedrooms) — 16% of a median data scientist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in St. Louis, MO
- Software Developer — $129,030
- Database Architect — $122,310
- Computer Occupations, All Other — $108,450
- Information Security Analyst — $106,420
- Web Developer — $106,360
- Database Administrator — $104,650
- Computer Network Architect — $103,370
- Computer Programmer — $96,920
- Computer Systems Analyst — $96,290
- Software Quality Assurance Analyst and Tester — $94,590
- Network and Computer Systems Administrator — $88,940
- Computer Network Support Specialist — $75,060