Nurse Practitioner Salary in Indianapolis, IN
Nurse Practitioners in the Indianapolis-Carmel-Greenwood, IN metro area earn a median $130,460 a year — 1% less than the national median. After 2026 taxes, that is $96,616 take-home, or $8,051 a month.
Take-home pay calculator
Pre-filled with the median nurse practitioner salary in Indianapolis, IN. Enter your own offer to see your paycheck.
- Federal income tax$20,044
- Social Security (6.2%)$8,089
- Medicare (1.45%)$1,892
- Indiana income tax$3,819
- Take-home pay$96,616
Marginal rate: 24% federal + 2.95% state
Nurse Practitioner pay by experience in Indianapolis, IN
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $106,500 | $51.20 | $80,641 | $6,720 |
| 25th percentile | $122,720 | $59.00 | $91,554 | $7,630 |
| Median (50th) | $130,460 | $62.72 | $96,616 | $8,051 |
| 75th percentile | $136,130 | $65.45 | $100,325 | $8,360 |
| 90th percentile (top earners) | $152,090 | $73.12 | $110,762 | $9,230 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Indiana resident, 2026 tax rules.
What $130,460 buys in Indianapolis, IN
Prices in Indianapolis, IN are 4.3% lower than the U.S. average (housing costs are 11% below the national average). Adjusted for local prices, a median nurse practitioner's $96,616 take-home pay has the buying power of $100,962 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Nurse Practitioner jobs are about as common in Indianapolis, IN as in the U.S. overall (location quotient 1.10).
Best-paying cities for nurse practitioners, adjusted for cost of living
Indianapolis, IN ranks #46 of 117 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $231,560 | $150,760 | $136,530 |
| 2 | San Francisco, CA | $219,080 | $143,890 | $124,458 |
| 3 | Killeen, TX | $138,670 | $106,047 | $116,366 |
| 4 | Tulsa, OK | $139,460 | $100,857 | $113,050 |
| 5 | Sioux Falls, SD | $130,390 | $100,388 | $110,765 |
| 6 | McAllen, TX | $122,550 | $95,029 | $110,634 |
| 7 | Las Vegas, NV | $144,060 | $109,731 | $109,496 |
| 8 | Fresno, CA | $166,570 | $111,690 | $109,330 |
| 46 | Indianapolis, IN | $130,460 | $96,616 | $100,962 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 117 metros →
Nurse Practitioner salaries elsewhere in Indiana
- Fort Wayne, IN — $127,050
Frequently asked questions
How much does a nurse practitioner make in Indianapolis, IN?
The median nurse practitioner salary in the Indianapolis-Carmel-Greenwood, IN metro area is $130,460 a year, or about $62.72 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $122,720 and $136,130.
What is a nurse practitioner’s take-home pay in Indianapolis, IN?
On the median $130,460 salary, a single filer living in Indiana takes home about $96,616 a year ($8,051 a month) after federal tax, Social Security, Medicare and $3,819 in Indiana taxes in 2026.
Is Indianapolis, IN a good place to work as a nurse practitioner?
Pay here is 1% below the national median of $132,300. Local prices are 4.3% below the U.S. average, so the take-home pay buys what $100,962 would in a typical U.S. city. Indianapolis, IN ranks #46 of 117 metro areas for cost-of-living-adjusted pay in this job.
Can a nurse practitioner afford rent in Indianapolis, IN?
HUD’s fair market rent for a one-bedroom in Indianapolis, IN is $1,242 a month ($1,454 for two bedrooms) — 15% of a median nurse practitioner’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in Indianapolis, IN
- Anesthesiologist — $239,200+
- Physicians, All Other — $239,200+
- General Internal Medicine Physician — $239,200+
- Family Medicine Physician — $239,200+
- Emergency Medicine Physician — $239,200+
- Pediatricians, General — $170,020
- Dentists, General — $166,120
- Pharmacist — $151,050
- Physician Assistant — $131,950
- Veterinarian — $127,850
- Physical Therapist — $103,770
- Occupational Therapist — $100,080