Nurse Practitioner Salary in Fresno, CA
Nurse Practitioners in the Fresno, CA metro area earn a median $166,570 a year — 26% more than the national median. After 2026 taxes, that is $111,690 take-home, or $9,307 a month.
Take-home pay calculator
Pre-filled with the median nurse practitioner salary in Fresno, CA. Enter your own offer to see your paycheck.
- Federal income tax$28,711
- Social Security (6.2%)$10,327
- Medicare (1.45%)$2,415
- California income tax$11,261
- CA State Disability Insurance (SDI)$2,165
- Take-home pay$111,690
Marginal rate: 24% federal + 9.30% state
Nurse Practitioner pay by experience in Fresno, CA
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $129,300 | $62.16 | $90,166 | $7,514 |
| 25th percentile | $138,900 | $66.78 | $95,710 | $7,976 |
| Median (50th) | $166,570 | $80.08 | $111,690 | $9,307 |
| 75th percentile | $191,270 | $91.96 | $126,374 | $10,531 |
| 90th percentile (top earners) | $212,320 | $102.08 | $139,724 | $11,644 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, California resident, 2026 tax rules.
What $166,570 buys in Fresno, CA
Prices in Fresno, CA are 2.2% higher than the U.S. average (housing costs are 4% below the national average). Adjusted for local prices, a median nurse practitioner's $111,690 take-home pay has the buying power of $109,330 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Nurse Practitioner jobs are less concentrated in Fresno, CA than nationally (location quotient 0.57), so openings may be scarcer.
Best-paying cities for nurse practitioners, adjusted for cost of living
Fresno, CA ranks #8 of 117 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $231,560 | $150,760 | $136,530 |
| 2 | San Francisco, CA | $219,080 | $143,890 | $124,458 |
| 3 | Killeen, TX | $138,670 | $106,047 | $116,366 |
| 4 | Tulsa, OK | $139,460 | $100,857 | $113,050 |
| 5 | Sioux Falls, SD | $130,390 | $100,388 | $110,765 |
| 6 | McAllen, TX | $122,550 | $95,029 | $110,634 |
| 7 | Las Vegas, NV | $144,060 | $109,731 | $109,496 |
| 8 | Fresno, CA | $166,570 | $111,690 | $109,330 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 117 metros →
Nurse Practitioner salaries elsewhere in California
- San Jose, CA — $231,560
- San Francisco, CA — $219,080
- Sacramento, CA — $172,010
- Riverside, CA — $169,920
- San Diego, CA — $163,860
- Los Angeles, CA — $161,470
Frequently asked questions
How much does a nurse practitioner make in Fresno, CA?
The median nurse practitioner salary in the Fresno, CA metro area is $166,570 a year, or about $80.08 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $138,900 and $191,270.
What is a nurse practitioner’s take-home pay in Fresno, CA?
On the median $166,570 salary, a single filer living in California takes home about $111,690 a year ($9,307 a month) after federal tax, Social Security, Medicare and $13,427 in California taxes in 2026.
Is Fresno, CA a good place to work as a nurse practitioner?
Pay here is 26% above the national median of $132,300. Local prices are 2.2% above the U.S. average, so the take-home pay buys what $109,330 would in a typical U.S. city. Fresno, CA ranks #8 of 117 metro areas for cost-of-living-adjusted pay in this job.
Can a nurse practitioner afford rent in Fresno, CA?
HUD’s fair market rent for a one-bedroom in Fresno, CA is $1,315 a month ($1,625 for two bedrooms) — 14% of a median nurse practitioner’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in Fresno, CA
- Physicians, All Other — $239,200+
- Pharmacist — $169,160
- Registered Nurse — $125,420
- Physical Therapist — $123,820
- Speech-Language Pathologist — $110,960
- Radiologic Technologist and Technician — $107,350
- Dental Hygienist — $101,730
- Respiratory Therapist — $83,340
- Licensed Practical and Licensed Vocational Nurse — $75,580
- Surgical Technologist — $64,380
- Clinical Laboratory Technologist and Technician — $62,160
- Psychiatric Technician — $53,680