Nurse Practitioner Salary in Jackson, MS

Nurse Practitioners in the Jackson, MS metro area earn a median $124,730 a year — 6% less than the national median. After 2026 taxes, that is $92,262 take-home, or $7,688 a month.

Median salary
$124,730
$59.97 per hour
Typical range
$99,480 – $156,480
10th to 90th percentile
Jobs in Jackson, MS
1,310
2.34× national concentration

Take-home pay calculator

Pre-filled with the median nurse practitioner salary in Jackson, MS. Enter your own offer to see your paycheck.

Nurse Practitioner in Jackson, MS
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$92,262
per year · effective tax rate 26.0%
$7,688Monthly
$3,844Twice a month
$3,549Every 2 weeks
$44.36Hourly
  • Federal income tax$18,669
  • Social Security (6.2%)$7,733
  • Medicare (1.45%)$1,809
  • Mississippi income tax$4,257
  • Take-home pay$92,262

Marginal rate: 24% federal + 4.00% state

Nurse Practitioner pay by experience in Jackson, MS

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$99,480$47.83$75,567$6,297
25th percentile$109,360$52.58$82,122$6,844
Median (50th)$124,730$59.97$92,262$7,688
75th percentile$134,020$64.43$98,240$8,187
90th percentile (top earners)$156,480$75.23$112,693$9,391

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Mississippi resident, 2026 tax rules.

What $124,730 buys in Jackson, MS

Prices in Jackson, MS are 11.0% lower than the U.S. average (housing costs are 35% below the national average). Adjusted for local prices, a median nurse practitioner's $92,262 take-home pay has the buying power of $103,609 in a typical American city.

1-bedroom rent
$1,045
14% of monthly take-home
2-bedroom rent
$1,229
16% of monthly take-home
Left after 1-BR rent
$6,643
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Jackson, MS has 2.3× the national concentration of nurse practitioner jobs — a strong local market for this occupation.

Best-paying cities for nurse practitioners, adjusted for cost of living

Jackson, MS ranks #33 of 117 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1San Jose, CA $231,560$150,760$136,530
2San Francisco, CA $219,080$143,890$124,458
3Killeen, TX $138,670$106,047$116,366
4Tulsa, OK $139,460$100,857$113,050
5Sioux Falls, SD $130,390$100,388$110,765
6McAllen, TX $122,550$95,029$110,634
7Las Vegas, NV $144,060$109,731$109,496
8Fresno, CA $166,570$111,690$109,330
33Jackson, MS$124,730$92,262$103,609

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 117 metros →

Nurse Practitioner salaries elsewhere in Mississippi

Frequently asked questions

How much does a nurse practitioner make in Jackson, MS?

The median nurse practitioner salary in the Jackson, MS metro area is $124,730 a year, or about $59.97 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $109,360 and $134,020.

What is a nurse practitioner’s take-home pay in Jackson, MS?

On the median $124,730 salary, a single filer living in Mississippi takes home about $92,262 a year ($7,688 a month) after federal tax, Social Security, Medicare and $4,257 in Mississippi taxes in 2026.

Is Jackson, MS a good place to work as a nurse practitioner?

Pay here is 6% below the national median of $132,300. Local prices are 11.0% below the U.S. average, so the take-home pay buys what $103,609 would in a typical U.S. city. Jackson, MS ranks #33 of 117 metro areas for cost-of-living-adjusted pay in this job.

Can a nurse practitioner afford rent in Jackson, MS?

HUD’s fair market rent for a one-bedroom in Jackson, MS is $1,045 a month ($1,229 for two bedrooms) — 14% of a median nurse practitioner’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in Jackson, MS

Cost of living & all salaries in Jackson, MS →