Pharmacist Salary in Durham, NC

Pharmacists in the Durham-Chapel Hill, NC metro area earn a median $141,360 a year — 0% more than the national median. After 2026 taxes, that is $102,754 take-home, or $8,563 a month.

Median salary
$141,360
$67.96 per hour
Typical range
$102,870 – $165,740
10th to 90th percentile
Jobs in Durham, NC
1,150
1.62× national concentration

Take-home pay calculator

Pre-filled with the median pharmacist salary in Durham, NC. Enter your own offer to see your paycheck.

Pharmacist in Durham, NC
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$102,754
per year · effective tax rate 27.3%
$8,563Monthly
$4,281Twice a month
$3,952Every 2 weeks
$49.40Hourly
  • Federal income tax$22,660
  • Social Security (6.2%)$8,764
  • Medicare (1.45%)$2,050
  • North Carolina income tax$5,132
  • Take-home pay$102,754

Marginal rate: 24% federal + 3.99% state

Pharmacist pay by experience in Durham, NC

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$102,870$49.46$77,603$6,467
25th percentile$133,500$64.18$97,695$8,141
Median (50th)$141,360$67.96$102,754$8,563
75th percentile$164,900$79.28$117,904$9,825
90th percentile (top earners)$165,740$79.68$118,445$9,870

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, North Carolina resident, 2026 tax rules.

What $141,360 buys in Durham, NC

Prices in Durham, NC are 2.4% lower than the U.S. average (housing costs are 1% below the national average). Adjusted for local prices, a median pharmacist's $102,754 take-home pay has the buying power of $105,311 in a typical American city.

1-bedroom rent
$1,456
17% of monthly take-home
2-bedroom rent
$1,660
19% of monthly take-home
Left after 1-BR rent
$7,107
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Durham, NC has 1.6× the national concentration of pharmacist jobs — a strong local market for this occupation.

Best-paying cities for pharmacists, adjusted for cost of living

Durham, NC ranks #67 of 120 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Rochester, MN $164,250$113,470$124,938
2Sioux Falls, SD $148,330$112,650$124,295
3McAllen, TX $137,700$105,384$122,689
4San Antonio, TX $150,500$114,133$120,500
5Shreveport, LA $137,970$101,816$120,114
6San Jose, CA $199,040$131,343$118,945
7Spartanburg, SC $153,610$108,199$118,833
8Fargo, ND $142,040$106,840$117,573
67Durham, NC$141,360$102,754$105,311

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →

Pharmacist salaries elsewhere in North Carolina

Frequently asked questions

How much does a pharmacist make in Durham, NC?

The median pharmacist salary in the Durham-Chapel Hill, NC metro area is $141,360 a year, or about $67.96 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $133,500 and $164,900.

What is a pharmacist’s take-home pay in Durham, NC?

On the median $141,360 salary, a single filer living in North Carolina takes home about $102,754 a year ($8,563 a month) after federal tax, Social Security, Medicare and $5,132 in North Carolina taxes in 2026.

Is Durham, NC a good place to work as a pharmacist?

Pay here is 0% above the national median of $140,910. Local prices are 2.4% below the U.S. average, so the take-home pay buys what $105,311 would in a typical U.S. city. Durham, NC ranks #67 of 120 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in Durham, NC?

HUD’s fair market rent for a one-bedroom in Durham, NC is $1,456 a month ($1,660 for two bedrooms) — 17% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in Durham, NC

Cost of living & all salaries in Durham, NC →