Nurse Practitioner Salary in Durham, NC
Nurse Practitioners in the Durham-Chapel Hill, NC metro area earn a median $132,300 a year — 0% more than the national median. After 2026 taxes, that is $96,923 take-home, or $8,077 a month.
Take-home pay calculator
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- Federal income tax$20,486
- Social Security (6.2%)$8,203
- Medicare (1.45%)$1,918
- North Carolina income tax$4,770
- Take-home pay$96,923
Marginal rate: 24% federal + 3.99% state
Nurse Practitioner pay by experience in Durham, NC
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $108,200 | $52.02 | $81,140 | $6,762 |
| 25th percentile | $123,970 | $59.60 | $91,562 | $7,630 |
| Median (50th) | $132,300 | $63.61 | $96,923 | $8,077 |
| 75th percentile | $147,160 | $70.75 | $106,487 | $8,874 |
| 90th percentile (top earners) | $167,060 | $80.32 | $119,295 | $9,941 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, North Carolina resident, 2026 tax rules.
What $132,300 buys in Durham, NC
Prices in Durham, NC are 2.4% lower than the U.S. average (housing costs are 1% below the national average). Adjusted for local prices, a median nurse practitioner's $96,923 take-home pay has the buying power of $99,335 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Durham, NC has 2.0× the national concentration of nurse practitioner jobs — a strong local market for this occupation.
Best-paying cities for nurse practitioners, adjusted for cost of living
Durham, NC ranks #59 of 117 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $231,560 | $150,760 | $136,530 |
| 2 | San Francisco, CA | $219,080 | $143,890 | $124,458 |
| 3 | Killeen, TX | $138,670 | $106,047 | $116,366 |
| 4 | Tulsa, OK | $139,460 | $100,857 | $113,050 |
| 5 | Sioux Falls, SD | $130,390 | $100,388 | $110,765 |
| 6 | McAllen, TX | $122,550 | $95,029 | $110,634 |
| 7 | Las Vegas, NV | $144,060 | $109,731 | $109,496 |
| 8 | Fresno, CA | $166,570 | $111,690 | $109,330 |
| 59 | Durham, NC | $132,300 | $96,923 | $99,335 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 117 metros →
Nurse Practitioner salaries elsewhere in North Carolina
- Greensboro, NC — $132,230
- Winston, NC — $130,840
- Charlotte, NC — $130,310
- Asheville, NC — $127,770
- Raleigh, NC — $128,150
Frequently asked questions
How much does a nurse practitioner make in Durham, NC?
The median nurse practitioner salary in the Durham-Chapel Hill, NC metro area is $132,300 a year, or about $63.61 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $123,970 and $147,160.
What is a nurse practitioner’s take-home pay in Durham, NC?
On the median $132,300 salary, a single filer living in North Carolina takes home about $96,923 a year ($8,077 a month) after federal tax, Social Security, Medicare and $4,770 in North Carolina taxes in 2026.
Is Durham, NC a good place to work as a nurse practitioner?
Pay here is 0% above the national median of $132,300. Local prices are 2.4% below the U.S. average, so the take-home pay buys what $99,335 would in a typical U.S. city. Durham, NC ranks #59 of 117 metro areas for cost-of-living-adjusted pay in this job.
Can a nurse practitioner afford rent in Durham, NC?
HUD’s fair market rent for a one-bedroom in Durham, NC is $1,456 a month ($1,660 for two bedrooms) — 18% of a median nurse practitioner’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in Durham, NC
- Pharmacist — $141,360
- Physician Assistant — $132,670
- Physical Therapist — $100,240
- Radiologic Technologist and Technician — $80,430
- Licensed Practical and Licensed Vocational Nurse — $66,950
- Medical Records Specialist — $57,290
- Health Technologists and Technicians, All Other — $54,610
- Pharmacy Technician — $47,350