Pharmacist Salary in Knoxville, TN

Pharmacists in the Knoxville, TN metro area earn a median $132,460 a year — 6% less than the national median. After 2026 taxes, that is $101,802 take-home, or $8,484 a month.

Median salary
$132,460
$63.68 per hour
Typical range
$85,160 – $159,200
10th to 90th percentile
Jobs in Knoxville, TN
990
1.12× national concentration

Take-home pay calculator

Pre-filled with the median pharmacist salary in Knoxville, TN. Enter your own offer to see your paycheck.

Pharmacist in Knoxville, TN
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$101,802
per year · effective tax rate 23.1%
$8,484Monthly
$4,242Twice a month
$3,915Every 2 weeks
$48.94Hourly
  • Federal income tax$20,524
  • Social Security (6.2%)$8,213
  • Medicare (1.45%)$1,921
  • Tennessee income tax$0
  • Take-home pay$101,802

Marginal rate: 24% federal + 0.00% state

Pharmacist pay by experience in Knoxville, TN

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$85,160$40.94$68,740$5,728
25th percentile$123,000$59.13$95,337$7,945
Median (50th)$132,460$63.68$101,802$8,484
75th percentile$145,220$69.82$110,524$9,210
90th percentile (top earners)$159,200$76.54$120,079$10,007

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Tennessee resident, 2026 tax rules.

What $132,460 buys in Knoxville, TN

Prices in Knoxville, TN are 7.4% lower than the U.S. average (housing costs are 17% below the national average). Adjusted for local prices, a median pharmacist's $101,802 take-home pay has the buying power of $109,975 in a typical American city.

1-bedroom rent
$1,126
13% of monthly take-home
2-bedroom rent
$1,401
17% of monthly take-home
Left after 1-BR rent
$7,358
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Pharmacist jobs are about as common in Knoxville, TN as in the U.S. overall (location quotient 1.12).

Best-paying cities for pharmacists, adjusted for cost of living

Knoxville, TN ranks #40 of 120 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Rochester, MN $164,250$113,470$124,938
2Sioux Falls, SD $148,330$112,650$124,295
3McAllen, TX $137,700$105,384$122,689
4San Antonio, TX $150,500$114,133$120,500
5Shreveport, LA $137,970$101,816$120,114
6San Jose, CA $199,040$131,343$118,945
7Spartanburg, SC $153,610$108,199$118,833
8Fargo, ND $142,040$106,840$117,573
40Knoxville, TN$132,460$101,802$109,975

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →

Pharmacist salaries elsewhere in Tennessee

Frequently asked questions

How much does a pharmacist make in Knoxville, TN?

The median pharmacist salary in the Knoxville, TN metro area is $132,460 a year, or about $63.68 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $123,000 and $145,220.

What is a pharmacist’s take-home pay in Knoxville, TN?

On the median $132,460 salary, a single filer living in Tennessee takes home about $101,802 a year ($8,484 a month) after federal tax, Social Security, Medicare in 2026.

Is Knoxville, TN a good place to work as a pharmacist?

Pay here is 6% below the national median of $140,910. Local prices are 7.4% below the U.S. average, so the take-home pay buys what $109,975 would in a typical U.S. city. Knoxville, TN ranks #40 of 120 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in Knoxville, TN?

HUD’s fair market rent for a one-bedroom in Knoxville, TN is $1,126 a month ($1,401 for two bedrooms) — 13% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in Knoxville, TN

Cost of living & all salaries in Knoxville, TN →