Pharmacist Salary in Syracuse, NY

Pharmacists in the Syracuse, NY metro area earn a median $149,510 a year — 6% more than the national median. After 2026 taxes, that is $105,675 take-home, or $8,806 a month.

Median salary
$149,510
$71.88 per hour
Typical range
$114,060 – $171,850
10th to 90th percentile
Jobs in Syracuse, NY
740
1.18× national concentration

Take-home pay calculator

Pre-filled with the median pharmacist salary in Syracuse, NY. Enter your own offer to see your paycheck.

Pharmacist in Syracuse, NY
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$105,675
per year · effective tax rate 29.3%
$8,806Monthly
$4,403Twice a month
$4,064Every 2 weeks
$50.81Hourly
  • Federal income tax$24,616
  • Social Security (6.2%)$9,270
  • Medicare (1.45%)$2,168
  • New York income tax$7,781
  • Take-home pay$105,675

Marginal rate: 24% federal + 5.90% state

Pharmacist pay by experience in Syracuse, NY

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$114,060$54.84$83,382$6,948
25th percentile$135,060$64.93$96,651$8,054
Median (50th)$149,510$71.88$105,675$8,806
75th percentile$166,020$79.82$115,986$9,665
90th percentile (top earners)$171,850$82.62$119,627$9,969

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, New York resident, 2026 tax rules.

What $149,510 buys in Syracuse, NY

Prices in Syracuse, NY are 4.3% lower than the U.S. average (housing costs are 19% below the national average). Adjusted for local prices, a median pharmacist's $105,675 take-home pay has the buying power of $110,375 in a typical American city.

1-bedroom rent
$1,123
13% of monthly take-home
2-bedroom rent
$1,392
16% of monthly take-home
Left after 1-BR rent
$7,683
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Pharmacist jobs are about as common in Syracuse, NY as in the U.S. overall (location quotient 1.18).

Best-paying cities for pharmacists, adjusted for cost of living

Syracuse, NY ranks #37 of 120 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Rochester, MN $164,250$113,470$124,938
2Sioux Falls, SD $148,330$112,650$124,295
3McAllen, TX $137,700$105,384$122,689
4San Antonio, TX $150,500$114,133$120,500
5Shreveport, LA $137,970$101,816$120,114
6San Jose, CA $199,040$131,343$118,945
7Spartanburg, SC $153,610$108,199$118,833
8Fargo, ND $142,040$106,840$117,573
37Syracuse, NY$149,510$105,675$110,375

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →

Pharmacist salaries elsewhere in New York

Frequently asked questions

How much does a pharmacist make in Syracuse, NY?

The median pharmacist salary in the Syracuse, NY metro area is $149,510 a year, or about $71.88 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $135,060 and $166,020.

What is a pharmacist’s take-home pay in Syracuse, NY?

On the median $149,510 salary, a single filer living in New York takes home about $105,675 a year ($8,806 a month) after federal tax, Social Security, Medicare and $7,781 in New York taxes in 2026.

Is Syracuse, NY a good place to work as a pharmacist?

Pay here is 6% above the national median of $140,910. Local prices are 4.3% below the U.S. average, so the take-home pay buys what $110,375 would in a typical U.S. city. Syracuse, NY ranks #37 of 120 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in Syracuse, NY?

HUD’s fair market rent for a one-bedroom in Syracuse, NY is $1,123 a month ($1,392 for two bedrooms) — 13% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in Syracuse, NY

Cost of living & all salaries in Syracuse, NY →