Nurse Practitioner Salary in Portland, ME
Nurse Practitioners in the Portland-South Portland, ME metro area earn a median $130,240 a year — 2% less than the national median. After 2026 taxes, that is $92,469 take-home, or $7,706 a month.
Take-home pay calculator
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- Federal income tax$19,992
- Social Security (6.2%)$8,075
- Medicare (1.45%)$1,888
- Maine income tax$7,816
- Take-home pay$92,469
Marginal rate: 24% federal + 7.15% state
Nurse Practitioner pay by experience in Portland, ME
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $107,820 | $51.84 | $78,468 | $6,539 |
| 25th percentile | $111,760 | $53.73 | $80,958 | $6,746 |
| Median (50th) | $130,240 | $62.62 | $92,469 | $7,706 |
| 75th percentile | $139,710 | $67.17 | $98,264 | $8,189 |
| 90th percentile (top earners) | $165,090 | $79.37 | $113,797 | $9,483 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Maine resident, 2026 tax rules.
What $130,240 buys in Portland, ME
Prices in Portland, ME are 1.9% higher than the U.S. average (housing costs are 1.05× the national average). Adjusted for local prices, a median nurse practitioner's $92,469 take-home pay has the buying power of $90,782 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Portland, ME has 1.2× the national concentration of nurse practitioner jobs — a strong local market for this occupation.
Best-paying cities for nurse practitioners, adjusted for cost of living
Portland, ME ranks #111 of 117 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $231,560 | $150,760 | $136,530 |
| 2 | San Francisco, CA | $219,080 | $143,890 | $124,458 |
| 3 | Killeen, TX | $138,670 | $106,047 | $116,366 |
| 4 | Tulsa, OK | $139,460 | $100,857 | $113,050 |
| 5 | Sioux Falls, SD | $130,390 | $100,388 | $110,765 |
| 6 | McAllen, TX | $122,550 | $95,029 | $110,634 |
| 7 | Las Vegas, NV | $144,060 | $109,731 | $109,496 |
| 8 | Fresno, CA | $166,570 | $111,690 | $109,330 |
| 111 | Portland, ME | $130,240 | $92,469 | $90,782 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 117 metros →
Frequently asked questions
How much does a nurse practitioner make in Portland, ME?
The median nurse practitioner salary in the Portland-South Portland, ME metro area is $130,240 a year, or about $62.62 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $111,760 and $139,710.
What is a nurse practitioner’s take-home pay in Portland, ME?
On the median $130,240 salary, a single filer living in Maine takes home about $92,469 a year ($7,706 a month) after federal tax, Social Security, Medicare and $7,816 in Maine taxes in 2026.
Is Portland, ME a good place to work as a nurse practitioner?
Pay here is 2% below the national median of $132,300. Local prices are 1.9% above the U.S. average, so the take-home pay buys what $90,782 would in a typical U.S. city. Portland, ME ranks #111 of 117 metro areas for cost-of-living-adjusted pay in this job.
Can a nurse practitioner afford rent in Portland, ME?
HUD’s fair market rent for a one-bedroom in Portland, ME is $1,548 a month ($1,968 for two bedrooms) — 20% of a median nurse practitioner’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in Portland, ME
- Physicians, All Other — $239,200+
- Pharmacist — $140,620
- Physician Assistant — $131,180
- Physical Therapist — $102,820
- Dental Hygienist — $98,880
- Registered Nurse — $88,470
- Occupational Therapist — $86,530
- Clinical Laboratory Technologist and Technician — $68,690
- Medical Records Specialist — $57,060
- Veterinary Technologist and Technician — $50,890
- Pharmacy Technician — $46,630