Pharmacist Salary in Greenville, SC
Pharmacists in the Greenville-Anderson-Greer, SC metro area earn a median $135,580 a year — 4% less than the national median. After 2026 taxes, that is $96,957 take-home, or $8,080 a month.
Take-home pay calculator
Pre-filled with the median pharmacist salary in Greenville, SC. Enter your own offer to see your paycheck.
- Federal income tax$21,273
- Social Security (6.2%)$8,406
- Medicare (1.45%)$1,966
- South Carolina income tax$6,978
- Take-home pay$96,957
Marginal rate: 24% federal + 6.00% state
Pharmacist pay by experience in Greenville, SC
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $73,610 | $35.39 | $57,355 | $4,780 |
| 25th percentile | $129,410 | $62.22 | $93,110 | $7,759 |
| Median (50th) | $135,580 | $65.18 | $96,957 | $8,080 |
| 75th percentile | $156,940 | $75.45 | $110,275 | $9,190 |
| 90th percentile (top earners) | $164,810 | $79.24 | $115,182 | $9,599 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, South Carolina resident, 2026 tax rules.
What $135,580 buys in Greenville, SC
Prices in Greenville, SC are 6.7% lower than the U.S. average (housing costs are 23% below the national average). Adjusted for local prices, a median pharmacist's $96,957 take-home pay has the buying power of $103,964 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Pharmacist jobs are about as common in Greenville, SC as in the U.S. overall (location quotient 0.99).
Best-paying cities for pharmacists, adjusted for cost of living
Greenville, SC ranks #78 of 120 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | Rochester, MN | $164,250 | $113,470 | $124,938 |
| 2 | Sioux Falls, SD | $148,330 | $112,650 | $124,295 |
| 3 | McAllen, TX | $137,700 | $105,384 | $122,689 |
| 4 | San Antonio, TX | $150,500 | $114,133 | $120,500 |
| 5 | Shreveport, LA | $137,970 | $101,816 | $120,114 |
| 6 | San Jose, CA | $199,040 | $131,343 | $118,945 |
| 7 | Spartanburg, SC | $153,610 | $108,199 | $118,833 |
| 8 | Fargo, ND | $142,040 | $106,840 | $117,573 |
| 78 | Greenville, SC | $135,580 | $96,957 | $103,964 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →
Pharmacist salaries elsewhere in South Carolina
- Spartanburg, SC — $153,610
- Charleston, SC — $145,950
- Columbia, SC — $133,850
Frequently asked questions
How much does a pharmacist make in Greenville, SC?
The median pharmacist salary in the Greenville-Anderson-Greer, SC metro area is $135,580 a year, or about $65.18 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $129,410 and $156,940.
What is a pharmacist’s take-home pay in Greenville, SC?
On the median $135,580 salary, a single filer living in South Carolina takes home about $96,957 a year ($8,080 a month) after federal tax, Social Security, Medicare and $6,978 in South Carolina taxes in 2026.
Is Greenville, SC a good place to work as a pharmacist?
Pay here is 4% below the national median of $140,910. Local prices are 6.7% below the U.S. average, so the take-home pay buys what $103,964 would in a typical U.S. city. Greenville, SC ranks #78 of 120 metro areas for cost-of-living-adjusted pay in this job.
Can a pharmacist afford rent in Greenville, SC?
HUD’s fair market rent for a one-bedroom in Greenville, SC is $1,155 a month ($1,288 for two bedrooms) — 14% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in Greenville, SC
- Dentists, General — $139,940
- Physician Assistant — $123,310
- Nurse Practitioner — $119,280
- Physical Therapist — $101,020
- Dental Hygienist — $85,290
- Registered Nurse — $81,400
- Radiologic Technologist and Technician — $68,700
- Surgical Technologist — $63,050
- Licensed Practical and Licensed Vocational Nurse — $61,960
- Clinical Laboratory Technologist and Technician — $53,070
- Medical Records Specialist — $53,040
- Veterinary Technologist and Technician — $45,740