Pharmacist Salary in Springfield, MO

Pharmacists in the Springfield, MO metro area earn a median $134,990 a year — 4% less than the national median. After 2026 taxes, that is $98,124 take-home, or $8,177 a month.

Median salary
$134,990
$64.90 per hour
Typical range
$79,700 – $161,750
10th to 90th percentile
Jobs in Springfield, MO
560
1.20× national concentration

Take-home pay calculator

Pre-filled with the median pharmacist salary in Springfield, MO. Enter your own offer to see your paycheck.

Pharmacist in Springfield, MO
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$98,124
per year · effective tax rate 27.3%
$8,177Monthly
$4,089Twice a month
$3,774Every 2 weeks
$47.18Hourly
  • Federal income tax$21,132
  • Social Security (6.2%)$8,369
  • Medicare (1.45%)$1,957
  • Missouri income tax$5,407
  • Take-home pay$98,124

Marginal rate: 24% federal + 4.70% state

Pharmacist pay by experience in Springfield, MO

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$79,700$38.32$62,090$5,174
25th percentile$128,580$61.82$94,045$7,837
Median (50th)$134,990$64.90$98,124$8,177
75th percentile$157,730$75.83$112,598$9,383
90th percentile (top earners)$161,750$77.76$115,157$9,596

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Missouri resident, 2026 tax rules.

What $134,990 buys in Springfield, MO

Prices in Springfield, MO are 11.4% lower than the U.S. average (housing costs are 34% below the national average). Adjusted for local prices, a median pharmacist's $98,124 take-home pay has the buying power of $110,769 in a typical American city.

1-bedroom rent
$868
11% of monthly take-home
2-bedroom rent
$1,074
13% of monthly take-home
Left after 1-BR rent
$7,309
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Springfield, MO has 1.2× the national concentration of pharmacist jobs — a strong local market for this occupation.

Best-paying cities for pharmacists, adjusted for cost of living

Springfield, MO ranks #34 of 120 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Rochester, MN $164,250$113,470$124,938
2Sioux Falls, SD $148,330$112,650$124,295
3McAllen, TX $137,700$105,384$122,689
4San Antonio, TX $150,500$114,133$120,500
5Shreveport, LA $137,970$101,816$120,114
6San Jose, CA $199,040$131,343$118,945
7Spartanburg, SC $153,610$108,199$118,833
8Fargo, ND $142,040$106,840$117,573
34Springfield, MO$134,990$98,124$110,769

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →

Pharmacist salaries elsewhere in Missouri

Frequently asked questions

How much does a pharmacist make in Springfield, MO?

The median pharmacist salary in the Springfield, MO metro area is $134,990 a year, or about $64.90 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $128,580 and $157,730.

What is a pharmacist’s take-home pay in Springfield, MO?

On the median $134,990 salary, a single filer living in Missouri takes home about $98,124 a year ($8,177 a month) after federal tax, Social Security, Medicare and $5,407 in Missouri taxes in 2026.

Is Springfield, MO a good place to work as a pharmacist?

Pay here is 4% below the national median of $140,910. Local prices are 11.4% below the U.S. average, so the take-home pay buys what $110,769 would in a typical U.S. city. Springfield, MO ranks #34 of 120 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacist afford rent in Springfield, MO?

HUD’s fair market rent for a one-bedroom in Springfield, MO is $868 a month ($1,074 for two bedrooms) — 11% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in Springfield, MO

Cost of living & all salaries in Springfield, MO →