Pharmacist Salary in St. Louis, MO
Pharmacists in the St. Louis, MO-IL metro area earn a median $138,530 a year — 2% less than the national median. After 2026 taxes, that is $100,378 take-home, or $8,365 a month.
Take-home pay calculator
Pre-filled with the median pharmacist salary in St. Louis, MO. Enter your own offer to see your paycheck.
- Federal income tax$21,981
- Social Security (6.2%)$8,589
- Medicare (1.45%)$2,009
- Missouri income tax$5,574
- Take-home pay$100,378
Marginal rate: 24% federal + 4.70% state
The St. Louis, MO-IL metro spans Missouri, Illinois. Pick the state you live in — state income tax follows your residence.
Pharmacist pay by experience in St. Louis, MO
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $111,110 | $53.42 | $82,711 | $6,893 |
| 25th percentile | $129,760 | $62.38 | $94,796 | $7,900 |
| Median (50th) | $138,530 | $66.60 | $100,378 | $8,365 |
| 75th percentile | $159,630 | $76.75 | $113,808 | $9,484 |
| 90th percentile (top earners) | $166,840 | $80.21 | $118,397 | $9,866 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Missouri resident, 2026 tax rules.
What $138,530 buys in St. Louis, MO
Prices in St. Louis, MO are 4.9% lower than the U.S. average (housing costs are 21% below the national average). Adjusted for local prices, a median pharmacist's $100,378 take-home pay has the buying power of $105,563 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Pharmacist jobs are about as common in St. Louis, MO as in the U.S. overall (location quotient 1.05).
Best-paying cities for pharmacists, adjusted for cost of living
St. Louis, MO ranks #65 of 120 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | Rochester, MN | $164,250 | $113,470 | $124,938 |
| 2 | Sioux Falls, SD | $148,330 | $112,650 | $124,295 |
| 3 | McAllen, TX | $137,700 | $105,384 | $122,689 |
| 4 | San Antonio, TX | $150,500 | $114,133 | $120,500 |
| 5 | Shreveport, LA | $137,970 | $101,816 | $120,114 |
| 6 | San Jose, CA | $199,040 | $131,343 | $118,945 |
| 7 | Spartanburg, SC | $153,610 | $108,199 | $118,833 |
| 8 | Fargo, ND | $142,040 | $106,840 | $117,573 |
| 65 | St. Louis, MO | $138,530 | $100,378 | $105,563 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 120 metros →
Pharmacist salaries elsewhere in Missouri
- Springfield, MO — $134,990
- Kansas City, MO — $139,460
Frequently asked questions
How much does a pharmacist make in St. Louis, MO?
The median pharmacist salary in the St. Louis, MO-IL metro area is $138,530 a year, or about $66.60 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $129,760 and $159,630.
What is a pharmacist’s take-home pay in St. Louis, MO?
On the median $138,530 salary, a single filer living in Missouri takes home about $100,378 a year ($8,365 a month) after federal tax, Social Security, Medicare and $5,574 in Missouri taxes in 2026.
Is St. Louis, MO a good place to work as a pharmacist?
Pay here is 2% below the national median of $140,910. Local prices are 4.9% below the U.S. average, so the take-home pay buys what $105,563 would in a typical U.S. city. St. Louis, MO ranks #65 of 120 metro areas for cost-of-living-adjusted pay in this job.
Can a pharmacist afford rent in St. Louis, MO?
HUD’s fair market rent for a one-bedroom in St. Louis, MO is $989 a month ($1,211 for two bedrooms) — 12% of a median pharmacist’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in St. Louis, MO
- Physicians, All Other — $239,200+
- Nurse Anesthetist — $232,300
- Dentists, General — $210,430
- Physician Assistant — $136,120
- Nurse Practitioner — $131,580
- Veterinarian — $122,460
- Physical Therapist — $100,600
- Diagnostic Medical Sonographer — $98,990
- Dental Hygienist — $97,650
- Occupational Therapist — $95,770
- Speech-Language Pathologist — $86,480
- Magnetic Resonance Imaging Technologist — $83,330