Clinical Laboratory Technologist and Technician Salary in St. Louis, MO
Clinical Laboratory Technologists and Technicians in the St. Louis, MO-IL metro area earn a median $61,830 a year — 2% less than the national median. After 2026 taxes, that is $49,892 take-home, or $4,158 a month.
Take-home pay calculator
Pre-filled with the median clinical laboratory technologist and technician salary in St. Louis, MO. Enter your own offer to see your paycheck.
- Federal income tax$5,240
- Social Security (6.2%)$3,833
- Medicare (1.45%)$897
- Missouri income tax$1,969
- Take-home pay$49,892
Marginal rate: 12% federal + 4.70% state
Living in St. Louis? City residents also pay St. Louis’s Earnings Tax — about $618 a year on this salary — which lowers take-home pay to $49,273 ($4,106 a month). Choose “St. Louis” under City income tax in the calculator. Suburban residents usually don’t pay it.
The St. Louis, MO-IL metro spans Missouri, Illinois. Pick the state you live in — state income tax follows your residence.
Got an offer somewhere else? Compare it with this one after taxes and rent →
Clinical Laboratory Technologist and Technician pay by experience in St. Louis, MO
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $38,400 | $18.46 | $32,167 | $2,681 |
| 25th percentile | $47,850 | $23.00 | $39,316 | $3,276 |
| Median (50th) | $61,830 | $29.73 | $49,892 | $4,158 |
| 75th percentile | $78,910 | $37.94 | $61,572 | $5,131 |
| 90th percentile (top earners) | $96,860 | $46.57 | $73,356 | $6,113 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Missouri resident, 2026 tax rules.
What $61,830 buys in St. Louis, MO
Prices in St. Louis, MO are 4.9% lower than the U.S. average (housing costs are 21% below the national average). Adjusted for local prices, a median clinical laboratory technologist and technician's $49,892 take-home pay has the buying power of $52,469 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
St. Louis, MO has 1.4× the national concentration of clinical laboratory technologist and technician jobs — a strong local market for this occupation.
Best-paying cities for clinical laboratory technologists and technicians, adjusted for cost of living
St. Louis, MO ranks #12 of 32 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | New York, NY | $96,930 | $72,342 | $64,268 |
| 2 | Cleveland, OH | $66,360 | $54,458 | $57,981 |
| 3 | Seattle, WA | $78,170 | $63,823 | $57,429 |
| 4 | Nashville, TN | $65,060 | $54,456 | $56,526 |
| 5 | Boston, MA | $79,480 | $60,990 | $56,334 |
| 6 | Cincinnati, OH | $65,370 | $53,689 | $56,296 |
| 7 | Chicago, IL | $73,960 | $57,345 | $55,355 |
| 8 | San Francisco, CA | $84,130 | $63,327 | $54,775 |
| 12 | St. Louis, MO | $61,830 | $49,892 | $52,469 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 32 metros →
About the job: clinical laboratory technologists and technicians
- Typical education
- Bachelor's degree
- Work experience
- None required
- On-the-job training
- None
- Job outlook, 2025–35
- +2.7% (about average)
Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.
Clinical Laboratory Technologist and Technician salaries elsewhere in Missouri
- Kansas City, MO — $59,230
Frequently asked questions
How much does a clinical laboratory technologist and technician make in St. Louis, MO?
The median clinical laboratory technologist and technician salary in the St. Louis, MO-IL metro area is $61,830 a year, or about $29.73 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $47,850 and $78,910.
What is a clinical laboratory technologist and technician’s take-home pay in St. Louis, MO?
On the median $61,830 salary, a single filer living in Missouri takes home about $49,892 a year ($4,158 a month) after federal tax, Social Security, Medicare and $1,969 in Missouri taxes in 2026.
Is St. Louis, MO a good place to work as a clinical laboratory technologist and technician?
Pay here is 2% below the national median of $62,930. Local prices are 4.9% below the U.S. average, so the take-home pay buys what $52,469 would in a typical U.S. city. St. Louis, MO ranks #12 of 32 metro areas for cost-of-living-adjusted pay in this job.
Can a clinical laboratory technologist and technician afford rent in St. Louis, MO?
HUD’s fair market rent for a one-bedroom in St. Louis, MO is $989 a month ($1,211 for two bedrooms) — 24% of a median clinical laboratory technologist and technician’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in St. Louis, MO
- Physicians, All Other — $239,200+
- Pharmacist — $138,530
- Nurse Practitioner — $131,580
- Physical Therapist — $100,600
- Registered Nurse — $83,180
- Licensed Practical and Licensed Vocational Nurse — $65,120
- Health Technologists and Technicians, All Other — $47,570
- Pharmacy Technician — $45,220