Updated · 2026 tax rules · Data: IRS, BLS, BEA, HUD · How we calculate

Pharmacy Technician Salary in St. Louis, MO

Pharmacy Technicians in the St. Louis, MO-IL metro area earn a median $45,220 a year — 1% less than the national median. After 2026 taxes, that is $37,326 take-home, or $3,111 a month.

Median salary
$45,220
$21.74 per hour
Typical range
$36,020 – $58,730
10th to 90th percentile
Jobs in St. Louis, MO
4,980
1.23× national concentration
▲13.0%
Pay trend: The median for pharmacy technicians in St. Louis, MO rose from $40,030 (May 2024) to $45,220 (May 2025). That beat inflation (2.4%), a real raise of about 10.6%.

Take-home pay calculator

Pre-filled with the median pharmacy technician salary in St. Louis, MO. Enter your own offer to see your paycheck.

Pharmacy Technician in St. Louis, MO
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$37,326
per year · effective tax rate 17.5%
$3,111Monthly
$1,555Twice a month
$1,436Every 2 weeks
$17.95Hourly
  • Federal income tax$3,246
  • Social Security (6.2%)$2,804
  • Medicare (1.45%)$656
  • Missouri income tax$1,188
  • Take-home pay$37,326

Marginal rate: 12% federal + 4.70% state

Living in St. Louis? City residents also pay St. Louis’s Earnings Tax — about $452 a year on this salary — which lowers take-home pay to $36,874 ($3,073 a month). Choose “St. Louis” under City income tax in the calculator. Suburban residents usually don’t pay it.

The St. Louis, MO-IL metro spans Missouri, Illinois. Pick the state you live in — state income tax follows your residence.

Got an offer somewhere else? Compare it with this one after taxes and rent →

Pharmacy Technician pay by experience in St. Louis, MO

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$36,020$17.32$30,366$2,531
25th percentile$37,280$17.92$31,320$2,610
Median (50th)$45,220$21.74$37,326$3,111
75th percentile$48,190$23.17$39,573$3,298
90th percentile (top earners)$58,730$28.24$47,547$3,962

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Missouri resident, 2026 tax rules.

What $45,220 buys in St. Louis, MO

Prices in St. Louis, MO are 4.9% lower than the U.S. average (housing costs are 21% below the national average). Adjusted for local prices, a median pharmacy technician's $37,326 take-home pay has the buying power of $39,254 in a typical American city.

1-bedroom rent
$989
32% of monthly take-home
2-bedroom rent
$1,211
39% of monthly take-home
Left after 1-BR rent
$2,122
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

St. Louis, MO has 1.2× the national concentration of pharmacy technician jobs — a strong local market for this occupation.

Best-paying cities for pharmacy technicians, adjusted for cost of living

St. Louis, MO ranks #16 of 41 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1Seattle, WA $61,320$51,451$46,296
2Sacramento, CA $58,470$46,843$43,914
3Portland, OR $58,590$44,960$42,648
4San Antonio, TX $47,050$39,985$42,215
5San Francisco, CA $60,550$48,362$41,831
6Austin, TX $47,010$39,953$40,740
7Nashville, TN $45,950$39,101$40,587
8Kansas City, MO $45,360$37,432$40,448
16St. Louis, MO$45,220$37,326$39,254

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 41 metros →

About the job: pharmacy technicians

Prepare medications under the direction of a pharmacist. May measure, mix, count out, label, and record amounts and dosages of medications according to prescription orders.

Typical education
High school diploma or equivalent
Work experience
None required
On-the-job training
Moderate-term on-the-job training
Job outlook, 2025–35
+6.4% (faster than average)

Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.

Pharmacy Technician salaries elsewhere in Missouri

Frequently asked questions

How much does a pharmacy technician make in St. Louis, MO?

The median pharmacy technician salary in the St. Louis, MO-IL metro area is $45,220 a year, or about $21.74 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $37,280 and $48,190.

What is a pharmacy technician’s take-home pay in St. Louis, MO?

On the median $45,220 salary, a single filer living in Missouri takes home about $37,326 a year ($3,111 a month) after federal tax, Social Security, Medicare and $1,188 in Missouri taxes in 2026.

Is St. Louis, MO a good place to work as a pharmacy technician?

Pay here is 1% below the national median of $45,750. Local prices are 4.9% below the U.S. average, so the take-home pay buys what $39,254 would in a typical U.S. city. St. Louis, MO ranks #16 of 41 metro areas for cost-of-living-adjusted pay in this job.

Can a pharmacy technician afford rent in St. Louis, MO?

HUD’s fair market rent for a one-bedroom in St. Louis, MO is $989 a month ($1,211 for two bedrooms) — 32% of a median pharmacy technician’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Related jobs in St. Louis, MO

Cost of living & all salaries in St. Louis, MO →