Pharmacy Technician Salary in St. Louis, MO
Pharmacy Technicians in the St. Louis, MO-IL metro area earn a median $45,220 a year — 1% less than the national median. After 2026 taxes, that is $37,326 take-home, or $3,111 a month.
Take-home pay calculator
Pre-filled with the median pharmacy technician salary in St. Louis, MO. Enter your own offer to see your paycheck.
- Federal income tax$3,246
- Social Security (6.2%)$2,804
- Medicare (1.45%)$656
- Missouri income tax$1,188
- Take-home pay$37,326
Marginal rate: 12% federal + 4.70% state
Living in St. Louis? City residents also pay St. Louis’s Earnings Tax — about $452 a year on this salary — which lowers take-home pay to $36,874 ($3,073 a month). Choose “St. Louis” under City income tax in the calculator. Suburban residents usually don’t pay it.
The St. Louis, MO-IL metro spans Missouri, Illinois. Pick the state you live in — state income tax follows your residence.
Got an offer somewhere else? Compare it with this one after taxes and rent →
Pharmacy Technician pay by experience in St. Louis, MO
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $36,020 | $17.32 | $30,366 | $2,531 |
| 25th percentile | $37,280 | $17.92 | $31,320 | $2,610 |
| Median (50th) | $45,220 | $21.74 | $37,326 | $3,111 |
| 75th percentile | $48,190 | $23.17 | $39,573 | $3,298 |
| 90th percentile (top earners) | $58,730 | $28.24 | $47,547 | $3,962 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Missouri resident, 2026 tax rules.
What $45,220 buys in St. Louis, MO
Prices in St. Louis, MO are 4.9% lower than the U.S. average (housing costs are 21% below the national average). Adjusted for local prices, a median pharmacy technician's $37,326 take-home pay has the buying power of $39,254 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
St. Louis, MO has 1.2× the national concentration of pharmacy technician jobs — a strong local market for this occupation.
Best-paying cities for pharmacy technicians, adjusted for cost of living
St. Louis, MO ranks #16 of 41 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | Seattle, WA | $61,320 | $51,451 | $46,296 |
| 2 | Sacramento, CA | $58,470 | $46,843 | $43,914 |
| 3 | Portland, OR | $58,590 | $44,960 | $42,648 |
| 4 | San Antonio, TX | $47,050 | $39,985 | $42,215 |
| 5 | San Francisco, CA | $60,550 | $48,362 | $41,831 |
| 6 | Austin, TX | $47,010 | $39,953 | $40,740 |
| 7 | Nashville, TN | $45,950 | $39,101 | $40,587 |
| 8 | Kansas City, MO | $45,360 | $37,432 | $40,448 |
| 16 | St. Louis, MO | $45,220 | $37,326 | $39,254 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 41 metros →
About the job: pharmacy technicians
Prepare medications under the direction of a pharmacist. May measure, mix, count out, label, and record amounts and dosages of medications according to prescription orders.
- Typical education
- High school diploma or equivalent
- Work experience
- None required
- On-the-job training
- Moderate-term on-the-job training
- Job outlook, 2025–35
- +6.4% (faster than average)
Source: BLS Standard Occupational Classification and Employment Projections, 2025–35.
Pharmacy Technician salaries elsewhere in Missouri
- Kansas City, MO — $45,360
Frequently asked questions
How much does a pharmacy technician make in St. Louis, MO?
The median pharmacy technician salary in the St. Louis, MO-IL metro area is $45,220 a year, or about $21.74 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $37,280 and $48,190.
What is a pharmacy technician’s take-home pay in St. Louis, MO?
On the median $45,220 salary, a single filer living in Missouri takes home about $37,326 a year ($3,111 a month) after federal tax, Social Security, Medicare and $1,188 in Missouri taxes in 2026.
Is St. Louis, MO a good place to work as a pharmacy technician?
Pay here is 1% below the national median of $45,750. Local prices are 4.9% below the U.S. average, so the take-home pay buys what $39,254 would in a typical U.S. city. St. Louis, MO ranks #16 of 41 metro areas for cost-of-living-adjusted pay in this job.
Can a pharmacy technician afford rent in St. Louis, MO?
HUD’s fair market rent for a one-bedroom in St. Louis, MO is $989 a month ($1,211 for two bedrooms) — 32% of a median pharmacy technician’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in St. Louis, MO
- Physicians, All Other — $239,200+
- Pharmacist — $138,530
- Nurse Practitioner — $131,580
- Physical Therapist — $100,600
- Registered Nurse — $83,180
- Licensed Practical and Licensed Vocational Nurse — $65,120
- Clinical Laboratory Technologist and Technician — $61,830
- Health Technologists and Technicians, All Other — $47,570