Natural Sciences Manager Salary in Denver, CO
Natural Sciences Managers in the Denver-Aurora-Centennial, CO metro area earn a median $141,080 a year — 16% less than the national median. After 2026 taxes, that is $102,195 take-home, or $8,516 a month.
Take-home pay calculator
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- Federal income tax$22,593
- Social Security (6.2%)$8,747
- Medicare (1.45%)$2,046
- Colorado income tax$5,499
- Take-home pay$102,195
Marginal rate: 24% federal + 4.40% state
Natural Sciences Manager pay by experience in Denver, CO
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $83,310 | $40.05 | $64,481 | $5,373 |
| 25th percentile | $101,090 | $48.60 | $76,207 | $6,351 |
| Median (50th) | $141,080 | $67.83 | $102,195 | $8,516 |
| 75th percentile | $185,620 | $89.24 | $130,748 | $10,896 |
| 90th percentile (top earners) | $263,840+ | $126.85 | $181,367 | $15,114 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Colorado resident, 2026 tax rules.
What $141,080 buys in Denver, CO
Prices in Denver, CO are 5.8% higher than the U.S. average (housing costs are 1.47× the national average). Adjusted for local prices, a median natural sciences manager's $102,195 take-home pay has the buying power of $96,609 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Natural Sciences Manager jobs are about as common in Denver, CO as in the U.S. overall (location quotient 0.81).
Best-paying cities for natural sciences managers, adjusted for cost of living
Denver, CO ranks #27 of 33 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | Boston, MA | $239,200+ | $195,208 | $180,304 |
| 2 | San Jose, CA | $239,200+ | $168,514 | $152,608 |
| 3 | Worcester, MA | $212,600 | $147,797 | $144,160 |
| 4 | Seattle, WA | $203,150 | $151,247 | $136,095 |
| 5 | Durham, NC | $183,540 | $129,901 | $133,134 |
| 6 | San Francisco, CA | $225,230 | $147,276 | $127,387 |
| 7 | Charlotte, NC | $173,160 | $123,221 | $126,577 |
| 8 | Raleigh, NC | $173,510 | $123,446 | $125,764 |
| 27 | Denver, CO | $141,080 | $102,195 | $96,609 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 33 metros →
Frequently asked questions
How much does a natural sciences manager make in Denver, CO?
The median natural sciences manager salary in the Denver-Aurora-Centennial, CO metro area is $141,080 a year, or about $67.83 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $101,090 and $185,620.
What is a natural sciences manager’s take-home pay in Denver, CO?
On the median $141,080 salary, a single filer living in Colorado takes home about $102,195 a year ($8,516 a month) after federal tax, Social Security, Medicare and $5,499 in Colorado taxes in 2026.
Is Denver, CO a good place to work as a natural sciences manager?
Pay here is 16% below the national median of $167,220. Local prices are 5.8% above the U.S. average, so the take-home pay buys what $96,609 would in a typical U.S. city. Denver, CO ranks #27 of 33 metro areas for cost-of-living-adjusted pay in this job.
Can a natural sciences manager afford rent in Denver, CO?
HUD’s fair market rent for a one-bedroom in Denver, CO is $1,754 a month ($2,089 for two bedrooms) — 21% of a median natural sciences manager’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in Denver, CO
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- Financial Manager — $193,400
- Architectural and Engineering Manager — $191,440
- Marketing Manager — $182,470
- Sales Manager — $181,580
- Purchasing Manager — $180,000
- Managers, All Other — $175,980
- Human Resources Manager — $170,940
- Administrative Services Manager — $164,240
- Industrial Production Manager — $146,460
- Training and Development Manager — $144,370
- General and Operations Manager — $142,330