Nurse Practitioner Salary in Buffalo, NY
Nurse Practitioners in the Buffalo-Cheektowaga, NY metro area earn a median $132,220 a year — 0% less than the national median. After 2026 taxes, that is $94,878 take-home, or $7,906 a month.
Take-home pay calculator
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- Federal income tax$20,467
- Social Security (6.2%)$8,198
- Medicare (1.45%)$1,917
- New York income tax$6,761
- Take-home pay$94,878
Marginal rate: 24% federal + 5.90% state
Nurse Practitioner pay by experience in Buffalo, NY
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $104,470 | $50.23 | $77,201 | $6,433 |
| 25th percentile | $111,890 | $53.79 | $81,983 | $6,832 |
| Median (50th) | $132,220 | $63.57 | $94,878 | $7,906 |
| 75th percentile | $150,400 | $72.31 | $106,231 | $8,853 |
| 90th percentile (top earners) | $166,300 | $79.95 | $116,161 | $9,680 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, New York resident, 2026 tax rules.
What $132,220 buys in Buffalo, NY
Prices in Buffalo, NY are 4.2% lower than the U.S. average (housing costs are 19% below the national average). Adjusted for local prices, a median nurse practitioner's $94,878 take-home pay has the buying power of $98,992 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Nurse Practitioner jobs are about as common in Buffalo, NY as in the U.S. overall (location quotient 1.07).
Best-paying cities for nurse practitioners, adjusted for cost of living
Buffalo, NY ranks #64 of 117 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $231,560 | $150,760 | $136,530 |
| 2 | San Francisco, CA | $219,080 | $143,890 | $124,458 |
| 3 | Killeen, TX | $138,670 | $106,047 | $116,366 |
| 4 | Tulsa, OK | $139,460 | $100,857 | $113,050 |
| 5 | Sioux Falls, SD | $130,390 | $100,388 | $110,765 |
| 6 | McAllen, TX | $122,550 | $95,029 | $110,634 |
| 7 | Las Vegas, NV | $144,060 | $109,731 | $109,496 |
| 8 | Fresno, CA | $166,570 | $111,690 | $109,330 |
| 64 | Buffalo, NY | $132,220 | $94,878 | $98,992 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 117 metros →
Nurse Practitioner salaries elsewhere in New York
- New York, NY — $163,340
- Syracuse, NY — $132,010
- Kiryas Joel, NY — $151,740
- Albany, NY — $134,590
- Rochester, NY — $128,110
Frequently asked questions
How much does a nurse practitioner make in Buffalo, NY?
The median nurse practitioner salary in the Buffalo-Cheektowaga, NY metro area is $132,220 a year, or about $63.57 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $111,890 and $150,400.
What is a nurse practitioner’s take-home pay in Buffalo, NY?
On the median $132,220 salary, a single filer living in New York takes home about $94,878 a year ($7,906 a month) after federal tax, Social Security, Medicare and $6,761 in New York taxes in 2026.
Is Buffalo, NY a good place to work as a nurse practitioner?
Pay here is 0% below the national median of $132,300. Local prices are 4.2% below the U.S. average, so the take-home pay buys what $98,992 would in a typical U.S. city. Buffalo, NY ranks #64 of 117 metro areas for cost-of-living-adjusted pay in this job.
Can a nurse practitioner afford rent in Buffalo, NY?
HUD’s fair market rent for a one-bedroom in Buffalo, NY is $1,139 a month ($1,343 for two bedrooms) — 14% of a median nurse practitioner’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.
Related jobs in Buffalo, NY
- Pharmacist — $137,900
- Physician Assistant — $126,360
- Physicians, All Other — $108,510
- Registered Nurse — $99,060
- Physical Therapist — $95,800
- Respiratory Therapist — $86,720
- Radiologic Technologist and Technician — $83,090
- Speech-Language Pathologist — $82,890
- Dental Hygienist — $82,470
- Occupational Therapist — $81,560
- Clinical Laboratory Technologist and Technician — $78,050
- Surgical Technologist — $77,440