Registered Nurse Salary in Santa Fe, NM
Registered Nurses in the Santa Fe, NM metro area earn a median $100,790 a year — 3% more than the national median. After 2026 taxes, that is $76,128 take-home, or $6,344 a month.
Take-home pay calculator
Pre-filled with the median registered nurse salary in Santa Fe, NM. Enter your own offer to see your paycheck.
- Federal income tax$13,344
- Social Security (6.2%)$6,249
- Medicare (1.45%)$1,461
- New Mexico income tax$3,608
- Take-home pay$76,128
Marginal rate: 22% federal + 4.90% state
Registered Nurse pay by experience in Santa Fe, NM
| Percentile | Salary | Hourly | Take-home / yr | Per month |
|---|---|---|---|---|
| 10th percentile (entry level) | $74,300 | $35.72 | $58,774 | $4,898 |
| 25th percentile | $80,890 | $38.89 | $63,100 | $5,258 |
| Median (50th) | $100,790 | $48.46 | $76,128 | $6,344 |
| 75th percentile | $131,830 | $63.38 | $96,243 | $8,020 |
| 90th percentile (top earners) | $131,830 | $63.38 | $96,243 | $8,020 |
Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, New Mexico resident, 2026 tax rules.
What $100,790 buys in Santa Fe, NM
Prices in Santa Fe, NM are 1.2% lower than the U.S. average (housing costs are 1.08× the national average). Adjusted for local prices, a median registered nurse's $76,128 take-home pay has the buying power of $77,078 in a typical American city.
Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.
Registered Nurse jobs are about as common in Santa Fe, NM as in the U.S. overall (location quotient 0.81).
Best-paying cities for registered nurses, adjusted for cost of living
Santa Fe, NM ranks #84 of 370 metro areas once taxes and local prices are taken into account.
| # | Metro area | Median salary | Take-home | Real value* |
|---|---|---|---|---|
| 1 | San Jose, CA | $216,740 | $142,511 | $129,059 |
| 2 | Vallejo, CA | $203,290 | $134,031 | $123,555 |
| 3 | Santa Rosa, CA | $174,550 | $116,298 | $107,899 |
| 4 | Sacramento, CA | $171,460 | $114,514 | $107,353 |
| 5 | San Francisco, CA | $186,610 | $123,394 | $106,730 |
| 6 | Santa Cruz, CA | $170,960 | $114,225 | $103,939 |
| 7 | Yuba City, CA | $149,320 | $101,728 | $97,597 |
| 8 | Olympia, WA | $125,020 | $96,717 | $93,293 |
| 84 | Santa Fe, NM | $100,790 | $76,128 | $77,078 |
*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 370 metros →
Registered Nurse salaries elsewhere in New Mexico
- Albuquerque, NM — $96,040
- Farmington, NM — $83,070
- Las Cruces, NM — $83,310
Frequently asked questions
How much does a registered nurse make in Santa Fe, NM?
The median registered nurse salary in the Santa Fe, NM metro area is $100,790 a year, or about $48.46 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $80,890 and $131,830.
What is a registered nurse’s take-home pay in Santa Fe, NM?
On the median $100,790 salary, a single filer living in New Mexico takes home about $76,128 a year ($6,344 a month) after federal tax, Social Security, Medicare and $3,608 in New Mexico taxes in 2026.
Is Santa Fe, NM a good place to work as a registered nurse?
Pay here is 3% above the national median of $97,550. Local prices are 1.2% below the U.S. average, so the take-home pay buys what $77,078 would in a typical U.S. city. Santa Fe, NM ranks #84 of 370 metro areas for cost-of-living-adjusted pay in this job.
Can a registered nurse afford rent in Santa Fe, NM?
HUD’s fair market rent for a one-bedroom in Santa Fe, NM is $1,390 a month ($1,685 for two bedrooms) — 22% of a median registered nurse’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.