Registered Nurse Salary in Odessa, TX

Registered Nurses in the Odessa, TX metro area earn a median $81,370 a year — 17% less than the national median. After 2026 taxes, that is $66,074 take-home, or $5,506 a month.

Median salary
$81,370
$39.12 per hour
Typical range
$71,690 – $104,080
10th to 90th percentile
Jobs in Odessa, TX
1,140
0.65× national concentration

Take-home pay calculator

Pre-filled with the median registered nurse salary in Odessa, TX. Enter your own offer to see your paycheck.

Registered Nurse in Odessa, TX
Deductions, kids & local tax

2026 tax year. Federal brackets from IRS Rev. Proc. 2025-32.

Your take-home pay
$66,074
per year · effective tax rate 18.8%
$5,506Monthly
$2,753Twice a month
$2,541Every 2 weeks
$31.77Hourly
  • Federal income tax$9,071
  • Social Security (6.2%)$5,045
  • Medicare (1.45%)$1,180
  • Texas income tax$0
  • Take-home pay$66,074

Marginal rate: 22% federal + 0.00% state

Registered Nurse pay by experience in Odessa, TX

PercentileSalaryHourlyTake-home / yrPer month
10th percentile (entry level)$71,690$34.47$59,264$4,939
25th percentile$77,810$37.41$63,569$5,297
Median (50th)$81,370$39.12$66,074$5,506
75th percentile$103,130$49.58$81,382$6,782
90th percentile (top earners)$104,080$50.04$82,050$6,838

Wages: BLS Occupational Employment and Wage Statistics, May 2025. Take-home: single filer, Texas resident, 2026 tax rules.

What $81,370 buys in Odessa, TX

Prices in Odessa, TX are 6.1% lower than the U.S. average (housing costs are 10% below the national average). Adjusted for local prices, a median registered nurse's $66,074 take-home pay has the buying power of $70,369 in a typical American city.

1-bedroom rent
$1,269
23% of monthly take-home
2-bedroom rent
$1,595
29% of monthly take-home
Left after 1-BR rent
$4,237
per month for everything else

Rents: HUD Fair Market Rents, FY2026 (40th-percentile gross rent incl. utilities). Price levels: BEA Regional Price Parities, 2024.

Registered Nurse jobs are less concentrated in Odessa, TX than nationally (location quotient 0.65), so openings may be scarcer.

Best-paying cities for registered nurses, adjusted for cost of living

Odessa, TX ranks #240 of 370 metro areas once taxes and local prices are taken into account.

#Metro areaMedian salaryTake-homeReal value*
1San Jose, CA $216,740$142,511$129,059
2Vallejo, CA $203,290$134,031$123,555
3Santa Rosa, CA $174,550$116,298$107,899
4Sacramento, CA $171,460$114,514$107,353
5San Francisco, CA $186,610$123,394$106,730
6Santa Cruz, CA $170,960$114,225$103,939
7Yuba City, CA $149,320$101,728$97,597
8Olympia, WA $125,020$96,717$93,293
240Odessa, TX$81,370$66,074$70,369

*Take-home pay divided by the BEA price level, so every city is measured in U.S.-average dollars. See all 370 metros →

Registered Nurse salaries elsewhere in Texas

Frequently asked questions

How much does a registered nurse make in Odessa, TX?

The median registered nurse salary in the Odessa, TX metro area is $81,370 a year, or about $39.12 an hour, according to the Bureau of Labor Statistics (May 2025). The middle half earn between $77,810 and $103,130.

What is a registered nurse’s take-home pay in Odessa, TX?

On the median $81,370 salary, a single filer living in Texas takes home about $66,074 a year ($5,506 a month) after federal tax, Social Security, Medicare in 2026.

Is Odessa, TX a good place to work as a registered nurse?

Pay here is 17% below the national median of $97,550. Local prices are 6.1% below the U.S. average, so the take-home pay buys what $70,369 would in a typical U.S. city. Odessa, TX ranks #240 of 370 metro areas for cost-of-living-adjusted pay in this job.

Can a registered nurse afford rent in Odessa, TX?

HUD’s fair market rent for a one-bedroom in Odessa, TX is $1,269 a month ($1,595 for two bedrooms) — 23% of a median registered nurse’s monthly take-home pay. Financial planners usually suggest keeping rent under about 30%.

Cost of living & all salaries in Odessa, TX →